Included in the formulation
АТХ:D.08.A.C Biguanides and amidines
D.08.A. C.05 Polyhexanide
Pharmacodynamics:Antiseptic preparation, possesses bactericidal, antiprotozoal, fungicidal effect and a wide spectrum of antimicrobial activity. The drug is active against Pseudomonas aeruginosa, Escherichia fromoli, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, protozoa Entamoeba spp.
In the presence of blood and purulent discharge bactericidal effect is slightly reduced.
Pharmacokinetics:Not described.
Indications:Prevention and treatment of infected wounds and superficial soft tissue damage; washing the cavities using active drainage; prevention of infection during surgical reconstructive operations (irrigation of the operating field), antiseptic treatment of postoperative wounds (with the help of napkins); burn surface treatment; disinfection of surgical instruments, washing of implants.
XIX.T08-T14.T14.1 Open wound of unspecified area of the body
XIX.T20-T32.T30 Thermal and chemical burns, unspecified
XIX.T79.T79.3 Post-traumatic wound infection, not elsewhere classified
Contraindications:- Surgery on the brain, eyes, middle and inner ear
- Intraperitoneal lavage
- Washing of uninfected joints
- Pregnancy and lactation
- Childhood
- Hypersensitivity
Carefully:Operations on intact cartilaginous tissues.
Pregnancy and lactation:Category by FDA not determined. Do not use when pregnant and breast-feeding.
Dosing and Administration:Locally. Preliminary concentrate should be diluted to 0.1 or 0.2% concentration by adding to 1.0 ml Ringer's solution without lactate or 0.9% solution of sodium chloride 1.0 or 2.0 ml of concentrated Lavasept solution, respectively.
For washing and active drainage of wounds, a 0.1% solution is used; In case of infection of wounds with gram-negative flora - 0.2% solution.
Side effects:Skin rash; hives.
Special instructions:If hypersensitivity reaction develops, the application should be stopped immediately and symptomatic treatment (antihistamines) should be prescribed.
With prolonged use, the drug may damage intact cartilage. To avoid complications, it is not recommended to use a preparation for washing uninfected joints. If the product gets into intact cartilage, the wound should be rinsed with Ringer's solution without lactate or with saline.
When mixed with other solutions, cloudiness and precipitation should be avoided. Precipitated at low temperatures polyhexanide can be dissolved by heating the solution to 60 ° C.
Impact on the ability to drive vehicles and manage mechanisms not found.