Action mestnorazdrazhayuschee, anesthetic, distracting, antipruritic, antiseptic, sedative, vasodilatig.
The effect is mainly due to reflex reactions associated with irritation of sensitive nerve endings. Irritation of the skin or mucosal receptors stimulates the formation and release of endogenous biologically active agents (peptides, kinins, etc.), Involved in the regulation of pain, vascular permeability and other processes, providing analgesic, antipruritic effect and distracting.
Antiseptic activity is a consequence of indiscriminate action on microbial cells. Annoying (distracting) effect helps to reduce pain. Eliminates nasal congestion, presumably due to the effect on calcium channels sensitive nerve fibers. Local action is accompanied by vasoconstriction, coldness, passing a slight burning and tingling. Skin-visceral reflexes (reflex arc does not affect the brain) improve tissue trophism (innervation zones respectively).Reflexively changes the tone of vessels both superficial and deep located in tissues and internal organs. Irritating the receptors of the oral mucosa, causes the expansion of spasmodic coronary vessels and venotonic effect .. It is possible to use migraine - lubricating the skin of the temples with menthol pencil. With systemic action lowers blood pressure and has a calming effect on the central nervous system. After absorption, biotransformed in the liver and excreted in the urine and bile in the form of glucuronides.
Menthol is an integral part of a number of combined ready-made medicines.