Clinical and pharmacological group: & nbsp
Rehydrates
Included in the formulation
АТХ:A.06.A.D Laxative preparations with osmotic properties
A.06.A.D.18 Sorbitol
Pharmacodynamics:The stereoisomer of mannitol has an osmotic, laxative, detoxifying, sweetening, choleretic effect. In patients without violations of carbohydrate metabolism does not increase the level of glycemia. When ingested, it has a laxative and choleretic effect. With intravenous use increases diuresis.
Pharmacokinetics:After oral ingestion, up to 90% is absorbed in the gastrointestinal tract and utilized in the liver in the form of glycogen. About 5% of the brain tissue, myocardium and skeletal muscle are deposited.
Indications:It is used to treat hypovolemia, constipation, with any kind of shock, diseases of the gastrointestinal tract.
IV.E70-E90.E86 Reduction of the volume of the liquid
XI.K50-K52.K52 Other non-infectious gastroenteritis and colitis
XI.K55-K63.K59.0 Constipation
XI.K80-K87.K81.1 Chronic cholecystitis
XVIII.R50-R69.R57.1 Hypovolemic shock
XVIII.R50-R69.R57.8 Other types of shock
XIX.T79.T79.4 Traumatic shock
Contraindications:Individual intolerance.
Carefully:Hypersensitivity to the drug.
Pregnancy and lactation:Recommendations for FDA - Category B. It is used during pregnancy and lactation.
Dosing and Administration:Intravenously drip 20% solution of 10 ml / kg of weight: at a rate of 10-60 drops / min / kg.
Inside as a laxative: 30-40 g.
The highest daily dose: 200 ml / day - intravenously, inside - 40 g.
The highest single dose: 40 g.
Side effects:Allergic reactions.
Overdose:When ingested more than 40 g - Diarrhea, flatulence.
Interaction:Clinically significant interactions are not described.
Special instructions:It is not recommended to mix the preparation with phosphate and carbonate-containing solutions, as well as the use of sorbitol as a carrier solution for other drugs.