Included in the formulation
АТХ:C.10.A.X Other lipid-lowering drugs
Pharmacodynamics:The plant-derived agent contains predominantly steroidal saponins of furostanol type. It has a general tonic effect and stimulates some functions of the reproductive system. In men, restores and improves sexual libido, lengthening the time of erection. Stimulates spermatogenesis, increasing the number of spermatozoa and their mobility.
The mechanism of action of the extract of anchovy creeping is still unknown. It is assumed that the predominant substance - protodioscin - is metabolized in the body to dehydroepiandrosterone, which has a beneficial effect on the immunity, integrity of the cell membrane, erectile function and cholesterol metabolism. It is known that cholesterol is the starting material for the synthesis of all steroids, including dehydroepiandrosterone, testosterone and estradiol, which explains the hypolipidemic effect of the drug.Other active furostanol saponins, a part of Tribulus terrestris extract will likely modulate the effect of protodioscin.
It has hypolipidemic effect, and in patients with lipoproteinemia reduces total cholesterol and LDL cholesterol does not affect the values of serum triglycerides and HDL cholesterol, reduces blood clotting, increases intestinal tone and stimulates its contraction.
Pharmacokinetics:Pharmacological studies in humans have not been conducted. Tribulus herb extracts dry contains a complex of biologically active substances, in connection with which the conduct of pharmacokinetic studies is not possible.
Indications:Assign for the prevention and treatment of (independent and complex) disorders of the reproductive system in men and women. With erectile dysfunction for men to enhance libido, strength and duration of erection. Independently or in the treatment of certain forms of male infertility: infertility idiopathic oligoastenoteratospermii based (reduced quantity and quality of sperm in the selected sperm); infertility in the absence of improvement in sperm counts within 1 year after surgery for varicocele; immunologically conditioned infertility.
Women with menopausal and post-stress syndrome with detected neurovegetative and neuropsychic manifestations; with endocrine ovarian infertility.
If there is a violation of fat metabolism (dyslipoproteinemia) to reduce total cholesterol and LDL.
IV.E70-E90.E78 Disorders of lipoprotein metabolism and other lipidemia
IX.I70-I79.I70 Atherosclerosis
IX.I80-I89.I86.1 Varicose veins of the scrotum
XIV.N40-N51.N46 Male infertility
Contraindications:- hypersensitivity to all components of the drug;
- hyperplasia of the prostate;
- severe cardiovascular diseases (stroke, myocardial infarction during the last year) or severe, unstable and uncontrolled cardiovascular diseases (unstable angina, chronic heart failure with resting symptoms, sinus node weakness syndrome, or conduction disorders such as sinoatrial block atrioventricular block of II or III degree, bradycardia <50 beats per minute), and kidney disease (severe renal failure (creatinine clearance <25 ml / min or creatinine ≥ 180 μmol / L );
- allergy to peanut protein or soy;
- Pregnancy;
- the period of breastfeeding;
- age to 18 years.
Carefully:In the treatment of women with menopausal syndrome, it is necessary to move from a therapeutic dose to a maintenance dose gradually. After a sharp decrease in the effective dose or withdrawal of the drug, a repeated manifestation of a complex of climacteric symptoms is possible.
Pregnancy and lactation:It is not recommended for use during pregnancy and during breastfeeding because of the lack of clinical data confirming the safety of the drug during these periods.
Dosing and Administration:Tablets are taken orally after eating.
With a decrease in libido, impotence and infertility. In men with decreased libido, impotence and infertility, a dosage of 1-2 tablets is recommended 3 times a day. The duration of treatment is at least 90 days. The course of treatment can be repeated until a positive therapeutic effect is obtained. In women with endocrine infertility, a dosage of 1-2 tablets is recommended 3 times a day, from the 1 st to the 12 th day of the menstrual cycle. This course can be repeated periodically until the onset of pregnancy.
Climacteric and post-stroke syndrome in women.1-2 tablets 3 times a day for 60-90 days. After the improvement of the condition, gradually pass to the maintenance dose - 2 tablets per day for 1-2 years.
Dyslipidemia (to lower the level of total cholesterol): 2 tablets 3 times a day. Course - not less than 3 months. Repeated courses - on the advice of a doctor.
Side effects:Allergic reactions are possible. Irritant effect on the gastric mucosa (nausea).
In case of side effects, including those not described in the instructions, you should consult your doctor.
Overdose:Symptoms: there may be dyspeptic disorders (nausea, vomiting).
Treatment: symptomatic.
Interaction:It can increase the effect of diuretics and potentiate the antihypertensive effect of antihypertensive agents.
Simultaneous use with drugs that stimulate ovulation in women with infertility leads to a mutual enhancement of their effects.
Special instructions:Before you start taking the drug, you should consult your doctor.
If there is no effect on the background of taking the drug within 1 month, you should consult a doctor.
To avoid possible irritant effects of the drug on the gastric mucosait is recommended to take the drug after eating.
The shell of the drug contains soy lecithin. Patients who are allergic to peanut protein or soy can not use this drug because of the increased risk of severe allergic reactions (including anaphylactic shock).