Inside bronchitis, bronchiectasis, bronchiolitis, laryngitis, bronchial asthma, sinusitis, average otitis adults and children over 6 years - 200 mg 2-3 times a day; children aged 2 to 6 years - 200 mg 2 times a day or 100 mg 3 times a day (recommended - in the form of effervescent tablets), up to 2 years - 100 mg 2 times a day.
In cystic fibrosis, children over 6 years of age should take the drug 200 mg three times a day (600 mg per day). The dose should be increased gradually. Patients with a body weight of more than 30 kg with cystic fibrosis drug can be taken in a dose of up to 800 mg per day.
In newborn infants are used only for vital indications in a dose of 10 mg / kg under the strict supervision of a doctor.
Inside the initial dose of 140 mg / kg, then 70 mg / kg every 4 hours - up to 17 additional doses.
Intramuscularly adults - 300 mg once a day, children - 150 mg once a day.
Inhalation - 2-5 ml of 20% solution 3-4 times a day (for 15-20 minutes).
Locally - to flush the auditory canals, nasal passages (for 1 procedure - 1.5-3 ml of 10% solution).
It is recommended that after food intake.
For use as an antidote, the combined use of acetylcysteine and activated carbon, a loading dose of 140-235 mg / kg, followed by 70 mg / kg every 4 hours - up to 17 additional doses is recommended.