Clinical and pharmacological group: & nbsp

Hepatoprotectors

Included in the formulation
АТХ:

A.09.A.B.02   Betaine

Pharmacodynamics:

The drug is an antioxidant. Used as a methyl group donor in patients with homocystinuria.

Has hepatoprotective, choleretic, lipotropic act.

Activates metabolic methylation in the liver. Low toxicity, almost no side effects.

Pharmacokinetics:

There is no data on the pharmacokinetics of the drug.

Indications:

Dyskinesia of the biliary tract; dyspepsia with abundant food intake, rich in proteins and fats, excessive consumption of ethanol, irregular eating; fatty hepatosis; secondary hyperlipidemia; atheromatosis (as part of complex therapy).

I.B15-B19.B19   Viral hepatitis, unspecified

IV.E70-E90.E78.5   Hyperlipidemia, unspecified

XI.K20-K31.K30   Dyspepsia

Contraindications:

Hypersensitivity.

Carefully:

Use in children. It is necessary to carefully select the dose of the drug.

Pregnancy and lactation:

Recommendations of the FDA category C. Studies in humans and animals have not been conducted.

There is no information on the penetration into breast milk. However, its metabolic precursor, choline, is found in human breast milk in high concentrations. Do not use during pregnancy and lactation.

Dosing and Administration:

Inside, in the intervals between meals, 1-2 teaspoons of granules or one tablet is dissolved in half a glass of water and take up to 3 times a day.

Use in children. Inside. 1 month-18 years: 50 mg / kg twice a day.

Side effects:

Allergic reactions, vomiting, diarrhea.

Overdose:

Not described. Treatment is symptomatic.

Interaction:

Betaine, alkalinizing urine, can reduce the activity of antibiotics in the urine.

Special instructions:

Do not take it for a long time.

Has an alkaline reaction, can reduce the acidity of gastric juice.

There is not enough information to recommend or not recommend antioxidants (betaine including) patients with non-alcoholic fatty liver and / or steatohepatosis. Vitamin E can increase the activity of ALT in these patients.

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