Similar drugsTo uncover Dosage form: & nbspPills. Composition:One tablet contains:active substance (in terms of 100%) - nicotinoyl gamma aminobutyrate sodium - 0.05 g Excipients - potato starch - 0.05 g, magnesium hydroxycarbonate (magnesium carbonate basic) - 0.0375 g, calcium stearate - 0.0025 g, sucrose (sugar) - 0.1063 g, talc - 0.0037 g. Description:Tablets of white color, flat-cylindrical form with a facet and a risk, "marbling" is supposed. Pharmacotherapeutic group:Nootropic agent. Pharmacodynamics:Nootropic agent, dilates the vessels of the brain. It also has a tranquilizing, psychostimulating, antiaggregant and antioxidant effect. Improves the functional state of the brain due to the normalization of tissue metabolism and effects on cerebral circulation (increases the volume and linear speed of cerebral blood flow, reduces the resistance of cerebral vessels, inhibits platelet aggregation, improves microcirculation).At the course reception increases physical and mental efficiency, reduces headache, improves memory, normalizes sleep; contributes to the reduction or disappearance of feelings of anxiety, tension, fear; improves the condition of patients with motor and speech disorders. Pharmacokinetics:Absorption is fast and complete.It penetrates the blood-brain barrier, it is retained for a long time in the tissues of the body. Bioavailability - 50 - 88%. It is excreted mainly by the kidneys in unchanged form. Half-life is 0.51 hours. Indications:Chronic cerebrovascular: a failure of moderate severity, depressive disorders in old age.As part of complex therapy for the prevention of migraine attacks.B complex therapy of dystonia syndrome, accompanied by anxiety, fear, increased irritability, emotional lability.As part of a comprehensive treatment - to stop acute alcohol intoxication, with chronic alcoholism - to reduce asthenic, asthenoneurotic, postpsychotic, pre-recurrent conditions, as well as alcoholic encephalopathy.Improving the tolerance of physical and mental loads (to persons in tense and extreme conditions of activity); to restore the physical performance of athletes (to increase resistance to physical and mental stress).In urological practice: in children older than 3 years - to improve the adaptive function of the bladder (reduce detoxification hypoxia); in adults with urinary disorders - to improve the adaptive function of the bladder (reduce detoxification hypoxia). Contraindications:Hypersensitivity to the components of the drug, chronic renal failure.Because the preparation contains sucrose: a deficiency of sugarase / isomaltase, intolerance to fructose, glucose-galactose malabsorption.The drug is contraindicated in children for all indications, except for disorders of urination, in which it is used from 3 years. Pregnancy and lactation:The drug is contraindicated for use in pregnancy and during breastfeeding. Dosing and Administration:Inside, regardless of food intake.For chronic cerebrovascular insufficiency of moderate severity, a single dose of 0.025-0.05 grams 2 to 3 times a day, a daily dose of 0.05 to 0.15 g. The course of treatment is 1-2 months. Repeated course - after 5-6 months.With depressive disorders in the elderly - 0.025 - 0.2 g / day for 2-3 doses, the optimal dose - 0.05 - 0.125 g / day, for 1.5-3 months.For prevention of migraine attacks, 0.05 g 3 times a day, to stop the attack - 0.1 g once.With dystonia syndrome - 0,025-0,075 g / day, if necessary - up to 0,2 -0,3 g / day, for 1-1,5 months.For cupping acute alcohol intoxication - 0.1, - 0.2 g / day, short course 6-7 days; with chronic alcoholism - a daily dose of -0.025-0.05 g for 4-5 weeks.To improve the tolerance of physical and mental loads - 0,05-0,075: g / day for 1-1,5 months, to restore the physical performance of athletes in the same dose, during 2 weeks of training period.In urological practice: for children: over 3 years old - to improve the adaptive function of the bladder (hypoxia detrusora reduction) 0.025 g 2-3 times a day; for adults with urinary disorders - to improve the adaptive function of the bladder (reduce detoxification hypoxia) 0.05 g 3 times a day.The course of treatment is 1 month.Precautions for usePrecautions for the use of the drug are not studied Side effects:Allergic reactions (skin rash, itching), dizziness, headache, mild nausea, irritability, anxiety, agitation. Overdose:The lethal dose for a person is unknown. Too high doses can cause side effects, mainly nausea, vomiting and dizziness.During overdose, only dose-dependent side effects may increase, since dose-related (eg, allergic reactions) occur regardless of the dose taken.In case of poisoning, symptomatic treatment should be used. Interaction:Shortens the time of action of barbiturates, enhances the action of opioid analgesics. Form release / dosage:Tablets of 50 mg. Packaging:For 10 tablets in a planar cell package.For 30 or 60 tablets in cans of light-protective glass or cans of polymer or polymer bottles.Each jar or bottle, 3 or 5 contour squares together with instructions for use, is placed in a pack of cardboard. Storage conditions:In dry, dark place at a temperature of no higher than 25 ° C.Keep out of the reach of children. Shelf life:3 years. Do not use after the expiration date printed on the package. Terms of leave from pharmacies:On prescription Registration number:LS-001488 Date of registration:08.09.2011 Expiration Date:Unlimited The owner of the registration certificate:NORTH STAR, CJSC NORTH STAR, CJSC Russia Manufacturer: & nbspNORTH STAR, CJSC Russia Information update date: & nbsp2016-12-16 Illustrated instructions × Illustrated instructions Instructions