Polidex with phenylephrine (Polydexa with phenylephrine)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Similar drugsTo uncover
Dosage form: & nbspnasal spray
Composition:

Per 100 ml:

active ingredients: neomycin sulfate 1 g, corresponds to 650 000 units; polymyxin B sulfate 1 000 000 units; dexamethasone metasulfobenzoate sodium 0.025 g; phenylephrine hydrochloride 0.250 g;

Excipients: methyl parahydroxybenzoate 0.100 g, lithium chloride 0.340 g, citric acid monohydrate 0.280 g, lithium hydroxide 0.100 g, macrogol 4000 5,000 g, polysorbate 80 0.200 g, purified water up to 100 ml.

Description:

A clear, colorless liquid.

Pharmacotherapeutic group:glucocorticosteroid for topical use + antibiotics (aminoglycoside + cyclic polypeptide) + alpha-adrenomimetic
ATX: & nbsp
  • Dexamethasone in combination with other drugs
    • Pharmacodynamics:

    Combination drug for topical application in otolaryngology. Has anti-inflammatory effect of dexamethasone on the nasal mucosa, antibacterial action of antibiotics neomycin and polymyxin B.

    Dexamethasone is well absorbed with topical application, its absorption increases with inflammation of the mucous membrane. In combination of these antibiotics, the spectrum of antibacterial action extends to the majority of gram-positive and gram-negative microorganisms causing infectious and inflammatory diseases of the nasal cavity and accessorysinuses.

    Indications:

    Inflammatory and infectious diseases of the nasal cavity, pharynx, paranasal sinuses:

    - acute and chronic rhinitis;

    - acute and chronic rhinopharyngitis;

    - sinusitis.

    Contraindications:

    - Suspicion of the closed-angle glaucoma;

    simultaneous use of monoamine oxidase inhibitors;

    - viral diseases;

    - kidney diseases accompanied by albuminuria, kidney failure;

    - Pregnancy;

    - the period of breastfeeding;

    - children's age (up to 2.5 years);

    - Hypersensitivity to the components of the drug.

    Carefully:In patients with hypertension, ischemic heart disease, hyperthyroidism.
    Pregnancy and lactation:

    Contraindicated for use during pregnancy and breastfeeding.

    Dosing and Administration:

    Adults: one injection every nostril 3-5 times a day.

    Children aged 2.5 to 18 years: one injection every nostril 3 times a day.

    Duration of treatment is 5-10 days.

    Side effects:

    Local allergic reactions are possible.

    In case of unusual reactions, consult a doctor about the advisability of further use of the drug.

    Overdose:Due to the low degree of absorption in the systemic blood flow, an overdose is unlikely.
    Interaction:

    Drug interaction is due to the content of phenylephrine.

    Phenylephrine reduces the hypotensive effect of diuretics and antihypertensive drugs (including methyldopa, mekamilamin, guanadrel, guanetidine). If this combination can not be avoided, then a doctor's observation is necessary.

    Clinically significant drug interactions with other drugs have not been identified.

    Special instructions:

    Avoid contact with the eyes. In case of accidental contact with the eyes and other mucous membranes, immediately wash with plenty of water.

    When using the bottle, keep it upright in a vertical position.

    Do not use to flush the paranasal sinuses.

    For athletes: the preparation contains components that can give positive for doping control.

    Effect on the ability to drive transp. cf. and fur:

    There is no evidence of a negative effect of the drug on the ability to drive and other vehicles.

    Form release / dosage:

    Spray nasal.

    Packaging:For 15 ml in polyethylene lightproof bottles with a spray tip with a polyethylene screw cap.
    Each bottle, together with instructions for use, is placed in a cardboard box.
    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    He Use at the expiration date indicated on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:П N015492 / 01
    Date of registration:15.12.2008 / 23.07.2015
    The owner of the registration certificate:Bouchard-Recordati LaboratoriesBouchard-Recordati Laboratories France
    Manufacturer: & nbsp
    Representation: & nbspRUSFIK LLC RUSFIK LLC Russia
    Information update date: & nbsp07.01.2016
    Illustrated instructions
      Instructions
      Up