Prenatsid (Prenacid)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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  • Prenatsid
    drops d / eye 
    SIIFI SpA     Italy
    • Dosage form: & nbspTOApli eye.
    Composition:

    Per 100 ml:

    Active ingredient: sodium phosphonate dezonide - 0.250 g.

    Excipients: potassium dihydrogen phosphate, sodium hydrogen phosphate dodecahydrate, sodium chloride, polysorbate-80, benzalkonium chloride, purified water.

    Description:BColorless, clear solution.
    Pharmacotherapeutic group:Glucocorticosteroid for topical application
    ATX: & nbsp

    D.07.A.B   Corticosteroids are moderately active (group II)

    S.01.B.A.11   Desonides

    Pharmacodynamics:

    Dezonide is a non-halogenated corticosteroid for topical application in ophthalmology. Has anti-inflammatory effect, reduces vascular permeability, chemotaxis, promotes stabilization of lysosomes, has vasoconstrictive effect in inflammation.

    Pharmacokinetics:

    With topical application, systemic absorption is low.

    Indications:

    Acute and chronic allergic and inflammatory processes:

    - inflammation of the anterior part of the eye (blepharitis, conjunctivitis, scleritis, deep keratitis without epithelial involvement, irit, iridocyclitis);

    - inflammation of the posterior segment of the eye (choroiditis, chorioretinitis, optic neuritis).

    Prevention and treatment of inflammatory phenomena in the postoperative and post-traumatic period.

    Contraindications:

    - Keratitis caused by Herpes simplex (treelike keratitis), chicken pox and other viral diseases of the eyelids, conjunctiva and cornea;

    - fungal diseases of the eyes;

    - acute purulent eye diseases (including barley);

    - damage to the integrity of the cornea;

    - tuberculosis of the eyes;

    - corneal epitheliopathy;

    - increased intraocular pressure, glaucoma;

    - hypersensitivity to any of the components of the drug;

    - Children under 18 years.

    Carefully:

    In the acute phase of chemical burn of the cornea and conjunctiva (until the complete removal of toxic substances and necrotic tissues), with the presence of thinning of the cornea.

    Pregnancy and lactation:

    Data of clinical trials regarding the use of the drug during pregnancy and during lactation are not available. The drug can be used only if the intended benefit to the mother exceeds the possible risk.

    If it is necessary to use lactation, breastfeeding should be stopped.

    Dosing and Administration:Bury 1-2 drops 3-4 times a day in the conjunctival sac.
    Side effects:

    Allergic reactions, tingling, burning in the place of application.

    With prolonged use, it is possible to increase intraocular pressure with the development of the glaucoma symptom complex with optic nerve atrophy and narrowing of the visual fields (therefore, when using preparations containing glucocorticosteroids, the intraocular pressure should be regularly measured for more than 10 days), perforation of the cornea, attachment of the fungal infection.

    With continued use for more than three months, cataracts can develop.

    Overdose:

    Overdose may cause local side effects.

    Interaction:

    Pharmacological interaction with other drugs is not known.

    Special instructions:

    The drug is not recommended for use with contact lenses. Before using the drug, remove contact lenses and re-dress them no earlier than 20-30 minutes.

    As a result of prolonged use of drops, intraocular pressure may increase. If the drug is used for two weeks or more, the intraocular pressure should be measured regularly.

    Corticosteroid therapy can mask the current bacterial or fungal infection.

    Effect on the ability to drive transp. cf. and fur:

    In view of possible lacrimation after instillation of the drug, it is not recommended to apply it directly before driving vehicles or servicing mechanical equipment.

    Form release / dosage:

    Eye drops, 0,25%.

    Packaging:

    For 10 ml of the solution in bottles of dark glass type III, sealed with a lid of low density polyethylene and a copolymer of ethylene and vinyl acetate and an aluminum cap for running in.

    1 cap-dropper made of low-density polyethylene and a copolymer of ethylene and vinyl acetate with a polyethylene tip, sealed in a bag of polyester / aluminum / polyethylene.

    For 1 bottle of the drug complete with 1 cap-dropper and instructions for use in a pack of cardboard.

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    After opening the vial, the drug should be used within 30 days.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:П N015185 / 02
    Date of registration:29.08.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:SIIFI SpASIIFI SpA Italy
    Manufacturer: & nbsp
    Representation: & nbspZAMBON SpA ZAMBON SpA Italy
    Information update date: & nbsp16.12.2016
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