REMAXOL® (Remaxol®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Similar drugsTo uncover
Dosage form: & nbspsolution for infusions
Composition:

Active components: succinic acid - 5.280 g; N-methylglucamine (meglumine) 8.725 g; riboxin (inosine) 2.0 g; methionine - 0.75 g; nicotinamide - 0.25 g.

Excipients: sodium chloride - 6.0 g; potassium chloride - 0.30 g; magnesium chloride (in terms of anhydrous) - 0.12 g; sodium hydroxide - 1.788 g; water for injection up to 1.0 liter.

Description:Transparent colorless liquid with a weak characteristic odor.
Pharmacotherapeutic group:Metabolic means
ATX: & nbsp
  • Preparations for the treatment of liver diseases
    • Pharmacodynamics:

    REMAXOL® is a balanced infusion solution with a hepatoprotective effect.

    Under the action of the drug, the transition of anaerobic processes into aerobic processes is accelerated, the energy supply of hepatocytes is improved, the synthesis of macroerges is increased, the resistance of hepatocyte membranes to lipid peroxidation is increased, the activity of antioxidant protection enzymes is restored. REMAXOL® reduces cytolysis, which is manifested in a decrease in indicator enzymes: aspartate aminotransferases, alanine aminotransferases.

    REMAXOL® helps reduce bilirubin and its fractions, improves the excretion of direct bilirubin in bile. Reduces the activity of excretory enzymes of hepatocytes - alkaline phosphatase and gamma-glutamyl transpeptidase, promotes the oxidation of cholesterol to bile acids.

    Pharmacokinetics:

    With intravenous drip introduction, the natural components that make up the body are quickly distributed in the tissues of the body, disposed of almost instantly. Metabolism products are excreted in the urine and do not accumulate in the body.

    Indications:

    Dysfunction of the liver due to acute or chronic damage to it (toxic, alcoholic, medicinal hepatitis).

    In the complex treatment of viral hepatitis (in addition to etiotropic therapy).

    Contraindications:

    Individual intolerance of the components of the drug, pregnancy, lactation period, children's age.

    Carefully:

    Nephrolithiasis, gout, hyperuricemia.

    Dosing and Administration:

    REMAXOL® is administered only intravenously drip in a daily dose of 400 ml to 800 ml for 3-12 days, depending on the severity of the disease. The rate of administration is 40 to 60 drops (2 to 3 ml) per minute.

    Side effects:

    With the rapid administration of the solution, undesirable reactions may occur (hyperemia of the skin of varying severity, heat, sore throat, dry mouth) that do not require drug withdrawal.

    Allergic reactions are possible in the form of allergic rash and itchy skin, which are eliminated using antihistamines.

    Rare undesirable reactions include the appearance of nausea, headache and dizziness.

    Due to the activation of aerobic processes in the body, the body can lower the glucose concentration and increase the uric acid content in the blood.

    Overdose:

    There is no information about drug overdose.

    Interaction:

    It is not recommended to mix in one vial with other drugs for intravenous administration.

    Form release / dosage:Solution for infusion.
    Packaging:

    Solution for infusions in glass bottles of 200 or 400 ml. Each bottle, along with instructions for medical use, is placed in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature of 0 to 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years. Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-009341/09
    Date of registration:19.11.2009
    The owner of the registration certificate:POLISAN NTPF, LLC POLISAN NTPF, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp27.11.2015
    Illustrated instructions
      Instructions
      Up