The incidence of side effects is classified according to the recommendations of the World Health Organization: very often - not less than 10%; often - not less than 1%, but less than 10%; infrequently - not less than 0,1%, but less than 1%; rarely - not less than 0.01%, but less than 0.1%; very rarely - less than 0.01%, including single messages; frequency is unknown - insufficient data for estimating the frequency of the phenomenon in the population.
Infections: often - pneumonia, influenza, tracheobronchitis, upper respiratory tract infections, urinary tract infections; infrequently - sinusitis, ear infections, viral infections, tonsillitis, inflammation of the subcutaneous tissue, otitis media, eye infection, onychomycosis, acarodermatitis, cystitis; rarely - chronic otitis media.
From the side of metabolism and nutrition: often - increase / decrease in appetite; infrequently - anorexia, polydipsia; very rarely diabetic ketoacidosis; frequency unknown - water intoxication.
On the part of the blood and lymphatic system: infrequently - anemia, thrombocytopenia; rarely - granulocytopenia; very rarely - neutropenia, thrombocytopenia; frequency unknown - agrunulocytosis.
From the immune system: infrequently - a hypersensitivity reaction; frequency unknown - anaphylactic reaction.
From the nervous system: very often - insomnia, parkinsonism (including extrapyramidal disorders, musculoskeletal rigidity, cogwheel syndrome, akinesia, bradykinesia, hypokinesia, muscle rigidity); anxiety, nervousness, confusion, lethargy, akathisia, tremor, sedation, dystonia (including muscle spasms, involuntary muscle contractions, muscle contractions, eyeball movements, tongue paralysis), lethargy, postural bleeding, dyskinesia (including muscle twitching, chorea and choreoathetosis), syncope, transient ischemic attack, depressed state, drooling, stroke, attention impairment; infrequent excitation, flattening of affect, sleep disturbance, weakening of libido, anorgasmia, lack of response to stimuli, impaired coordination, loss of consciousness, speech disorder, hypoesthesia, impaired movement, tardive dyskinesia, malignant neuroleptic syndrome, diabetic coma; very rarely - mania.
From the gastrointestinal tract: often - nausea, vomiting, diarrhea, constipation, abdominal pain, indigestion, dry mouth, discomfort in the stomach; infrequently - dysphagia, gastritis, fecal matter; rarely - intestinal obstruction, jaundice, pancreatitis, cheilitis, aptialism.
From the cardiovascular system (SSS): often - tachycardia; rarely - orthostatic hypotension, atrioventricular block, palpitations, sinus bradycardia, blockade branch gastrointestinal atrial bundle branch block, "tides"; rarely - stroke and transient ischemic attack (mainly in elderly patients with dementia associated with psychosis); unknown - venous thromboembolism.
From the side of the organ of vision: often - blurring of vision; infrequently - conjunctivitis, hyperemia of the eye, dry eyes, increased tear, orbital edema, photophobia; rarely - glaucoma, decreased visual acuity, rotational nystagmus.
From the side of the organ of hearing and labyrinth: infrequently - pain, "ringing" in the ears.
On the part of the respiratory system: often - shortness of breath, nosebleed, cough, nasal congestion, sore throat; infrequently - rhinitis, respiratory failure, dysphonia, "wheezing" breathing, aspiration pneumonia, productive cough, blockage of the respiratory tract, wet wheezes, swelling of the nose; very rarely - hyperventilation, sleep apnea syndrome.