Active substanceMesodiethylethylene dibenzenesulfonateMesodiethylethylene dibenzenesulfonate
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  • Sagenite®
    capsules inwards 
    NIZHFARM, JSC     Russia
  • Sagenite®
    pills inwards 
    NIZHFARM, JSC     Russia
  • Dosage form: & nbsppills.
    Composition:One tablet contains:
    active substance: sigetin (mesodiethylethylenedibenzenesulfonate dicalcium dihydrate) 100 mg;
    Excipients: starch, stearic acid, microcrystalline cellulose.
    Description:

    tablets white or almost white, flat-cylindrical.

    Pharmacotherapeutic group:Anti-climacteric
    ATX: & nbsp

    G.02.C.X   Other drugs for use in gynecology

    Pharmacodynamics:Participates in the implementation of positive and negative feedback in the hypothalamic-pituitary-ovarian system, has a stabilizing effect on the gonadotropic function of the pituitary and hypothalamic center, without having an estrogenic effect on the target organs; strengthens uterine contractions; increases placental blood flow; helps increase the concentration in the blood of beta-lipoproteins, increase the sensitivity of tissues to the action of insulin and the utilization of glucose.
    Indications:Climacteric syndrome (manifested by "hot flashes", increased sweating, sleep disorders, irritability, depression, forgetfulness,degenerative changes in the skin and mucous membranes - fragility of the nails, thinning of the skin, wrinkles, dystrophy of the urinary tract mucosa).
    Contraindications:Hypersensitivity, metrorrhagia.
    Carefully:Renal failure, impaired liver function, hyperlipoproteinemia.
    Pregnancy and lactation:During pregnancy and lactation is not applied.
    Dosing and Administration:Take inside, regardless of the time of ingestion, with menopausal disorders in women 1 tablet per day. Daily dose - up to 2 tablets a day. The course of treatment is 30-40 days.
    Side effects:In rare cases, nausea, vomiting, dizziness, allergic reactions (rashes, swelling of the eyelids) are possible; metrorrhagia, cholestatic jaundice.
    Interaction:Strengthens the action of diuretic, antiarrhythmic, antihypertensive drugs, anticoagulants. Weakens the effects of male sex hormones.
    Folic acid and thyroid drugs increase the effectiveness of Sagenite®.

    Packaging:
    • (10) - packings, cellular, outline (1) - packs, cardboard
    • (10) - packings, cellular, outline (3) - packs, cardboard
    Storage conditions:List B. In a dry and inaccessible place for children at a temperature of no higher than 25 ° C.
    Shelf life:2 years.
    Do not use after the expiration date.
    Terms of leave from pharmacies:On prescription
    Registration number:P N002222 / 01
    Date of registration:18.11.2008
    The owner of the registration certificate:NIZHFARM, JSC NIZHFARM, JSC Russia
    Representation: & nbspMAKIZ-PHARMA, LLCMAKIZ-PHARMA, LLCRussia
    Information update date: & nbsp03.08.2015
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