Active substanceSalbutamolSalbutamol Similar drugsTo uncover Astalin aerosol d / inhal. Cipla Ltd. India Ventolin® aerosol d / inhal. GlaxoSmithKline Trading, ZAO Russia Ventolin® Nebulas solution d / inhal. Aspen Pharma Petit Co., Ltd. Russia Salamol Steri-Neb solution d / inhal. AIVEX Pharmaceuticals Yukey Limited United Kingdom Salamol Eco Light Breath aerosol d / inhal. Norton Waterford, acting under the trade name Ivex Pharmaceuticals Ireland Ireland Salbutabs pills inwards NATIVA, LLC Russia Salbutamol aerosol d / inhal. MOSHIMFARM PREPARATES them. N.А.Semashko, OJSC Russia Salbutamol aerosol d / inhal. ALVILS, LTD. Russia Salbutamol aerosol d / inhal. BINNOFARM, CJSC Russia Salbutamol AB aerosol d / inhal. ALTAYVITAMINS, CJSC Russia Salbutamol aeronaut aerosol d / inhal. NATIVA, LLC Russia Salbutamol-MCPP aerosol d / inhal. MOSHIMFARM PREPARATES them. N.А.Semashko, OJSC Russia Salbutamol-native solution d / inhal. NATIVA, LLC Russia Salbutamol-SOLOfarm solution d / inhal. GROTEKS, LLC Russia Salbutamol-Teva aerosol d / inhal. Teva Pharmaceutical Enterprises Co., Ltd. Israel Salgim® powder d / inhal. PULMOMED, CJSC Russia Saltos® pills inwards PULMOMED, CJSC Russia Cibutocaps Cibutocaps capsules d / inhal. Teva Pharmaceutical Enterprises Co., Ltd. Israel Dosage form: & nbspPowder for inhalation dosed. Composition:1 inhalation dose contains the active substance: Salbutamol hemisuccinate 0.25 mg.Excipients: sodium benzoate 9.75 mg. Description:The fine crystalline powder is white or almost white in color. Pharmacotherapeutic group:Bronchodilator - beta2-adrenomimetic is selective. ATX: & nbspR.03.A.C Selective beta-2-adrenomimeticsR.03.A.C.02 Salbutamol Pharmacodynamics:Bronchodilator. Salgim is a stimulator of beta-2 adrenergic receptors.Bronchodilating effect is manifested as early as 4-6 minutes after inhalation of the drug, linearly increases, reaching a maximum after 20-40 minutes, the duration of action is 4-5 hours.In therapeutic doses also has a pronounced stimulating effect on beta-2 adrenoreceptors of blood vessels and myometrium. Virtually no effect on beta-1 adrenoreceptors of the heart. Inhibits the release of mast cells from histamine, leukotrienes and prostaglandin D2 and other biologically active substances for a long time. Indications:Bronchial asthma (for arresting asthma attacks), reversible bronchial obstruction (prevention and treatment), including chronic obstructive pulmonary disease. Contraindications:Hypersensitivity to the components of the drug, ischemic heart disease, severe heart failure, heart rhythm disturbances (paroxysmal tachycardia, polytopic ventricular extrasystole); myocarditis, heart defects, aortic stenosis, decompensated diabetes mellitus, glaucoma, epipriplets, pyloroduodenal stenosis, kidney and liver diseases with impaired function; pregnancy, simultaneous reception of non-selective beta-blockers. Carefully:Heart failure, arterial hypertension, hyperthyroidism, pheochromocytoma, lactation. Dosing and Administration:Salgim is inhaled using an individual portable inhaler Cyclochaler according to the instructions.For arresting an attack of bronchospasm, 250-500 μg of salbutamol hemisuccinate (1-2 inhalation doses). To control the course of bronchial asthma of mild severity - 1-2 inhalation doses 1-4 times a day; to monitor the flowbronchial asthma of moderate severity - 1-2 inhalation doses 1-4 times a day in combination with other anti-asthmatic drugs. For the prevention of asthma physical effort - for 20-30 minutes before the load - 1-2 inhalation doses per reception. Children, for the removal of an attack of bronchospasm: a single dose of 250 mcg; for prophylaxis - 250 mcg / day; the frequency of administration is 3-4 times. To preventbronchospasm, caused by physical exertion, 250 mcg, before the expected physical exertion. In case of unpleasant sensations in the mouth and perspiration in the throat after inhalation, rinse the mouth with water. Side effects:Feeling of inner anxiety and mild tremor of skeletal muscles, convulsions, palpitations, sleep disturbances, paradoxical bronchospasm, cough, flushing of the skin of the face, nervous tension, anxiety, headache, dizziness, tachycardia (in pregnancy - in the mother and in the fetus), agitation, indigestion , nasal congestion, irritation of the respiratory tract, dry mouth and throat, changes in taste, urine retention, sweating, hyperglycemia, increased free fatty acids in the blood, hypokalemia,angioedema, allergic reactions (urticaria, erythema, edema of the face), increase or decrease in blood pressure, arrhythmia, discomfort or chest pain, fatigue. Overdose:Symptoms: nausea, vomiting, agitation, hallucinations, tachycardia, cardiac rhythm disturbance, peripheral vascular dilatation, lowering blood pressure, hypoxemia, hypokalemia, hyperglycemia, lactic acidosis, muscle tremor, headache.Treatment. The withdrawal of the drug and the conduct of symptomatic therapy (the appointment of selective beta-adrenoblockers requires caution in patients with bronchial asthma because of the risk of developing severe bronchospasm). Interaction:Salgim is well combined with anti-asthmatic drugs of other pharmacological groups (glucocorticosteroids, membrane stabilizers, antihistamines, expectorants, mucolytics, cholinolytics, xanthines).Theophylline and other xanthines, when used simultaneously, increase the likelihood of developing tachyarrhythmias; means for inhalation anesthesia, levodopa severe ventricular arrhythmias.Monoamine oxidase inhibitors and tricyclic antidepressants increase the effect of salbutamol, which can lead to a sharp drop in blood pressure.It is not recommended simultaneous administration of salbutamol and nonselective beta-blockers (such as propranolol) in patients with bronchial asthma due to the risk of developing severe bronchospasm. Anticholinergics in the inhalation form, while using at the same time, can cause an increase in intraocular pressure. Diuretics and glucocorticosteroids increase the hypokalemic effect of salbutamol.Enhances the effect of stimulants of the central nervous system, a side effect on the heart of the thyroid hormones.In the case of an increase in the heart rate and, as a consequence, an increase in blood pressure against the background of salbutamol treatment, the need for nitrates and antihypertensive drugs increases.Increases the likelihood of developing extrasystole against the background of cardiac glycosides. Special instructions:Excessive use of salbutamol can lead to increased bronchospasm and a threat to the life of the patient,in connection with which between the doses of regular doses of the drug should take breaks in a few hours (6 hours). Reduction of these intervals can occur only in exceptional cases and under the supervision of a physician.If it is necessary to prescribe the drug during lactation, breastfeeding should be discontinued. Form release / dosage:Powder for inhalation dosed with 250 μg / dose in an inhaler Cyclocha-lehr. Packaging:For 1.0 g (100 doses) or 2.0 g (200 doses) of the drug in the inhaler "Ochal cycle". Inhaler in a sealed packet of polyethylene in a pack of cardboard with instructions for use. Storage conditions:List B. In a dry, the dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children. Shelf life:3 years. Do not use after expiry date. Terms of leave from pharmacies:On prescription Registration number:LSR-001933/07 Date of registration:06.08.2007 Expiration Date:Unlimited The owner of the registration certificate:PULMOMED, CJSC PULMOMED, CJSC Russia Manufacturer: & nbspPULMOMED, CJSC Russia Information update date: & nbsp2016-09-15 Illustrated instructions × Illustrated instructions Instructions