Hypersensitivity to the components of the drug, intestinal obstruction, pathological narrowing in the lumen of the gastrointestinal tract, abdominal pain of unknown origin,strangulated hernia, acute inflammatory diseases of the abdominal cavity, peritonitis, gastrointestinal and uterine bleeding, cystitis, water-electrolyte metabolism disorders, diabetes mellitus, pregnancy, the period of breastfeeding, children's age (under 18), sugar / isomaltase deficiency, fructose intolerance , glucose-galactose malabsorption.