Solcoderm (Solcoderm®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspsolution for external use
Composition:

1 ml of the preparation SOLKODERM contains:

Active components:

Nitric acid concentrated 70% (w / w) 580.66 mg

Acetic acid ice 99% 41.08 mg

Oxalic acid dihydrate 57.32 mg

Lactic acid 90% (w / w) 4.55 mg

Copper (II) nitrate trihydrate 0.048 mg

Auxiliary components:

Water purified to 1, 0 ml

Description:

Colorless or slightly yellowed transparent solution.

Pharmacotherapeutic group:Local necrotizing agent
ATX: & nbsp
  • Preparations with softening and protective action
    • Pharmacodynamics:

    Solcoderm is a solution containing concentrated acids, and is intended for external use in the treatment of benign surface skin lesions.

    With topical application on the affected areas of the skin, Solcoderm leads to immediate intravital fixation followed by mummification of pathologically altered tissue, with which the drug comes into contact.

    The immediate effect of the drug is expressed in the discoloration of the skin with the appearance of a characteristic pale gray or yellowish hue. Devitalized after the effect of the drug, the fabric is dehydrated and, as it mummifies, becomes dark brown in color.The resulting mummified scab spontaneously exfoliates after a few days or weeks.

    Pharmacokinetics:

    During therapy with Solcoderm, there is no systemic effect of the drug on the body.

    Indications:

    Solkoderm is intended only for external use in the treatment of the following benign skin changes:

    - Verruca vulgaris (common warts)

    - Verruca plantaris (plantar warts)

    - Condylomata acuminata (genital warts)

    - Naevus naevo-cellularis (nevokletochny nevus, tested for good quality)

    Contraindications:

    - The use of Solkoderm is strictly contraindicated in malignant skin lesions prone to metastasis, in particular, in malignant melanoma.

    - Solcoderm should not be used in patients with a pronounced tendency to form scar tissue.

    Solcoderm should not be used to remove freckles and keloid scars. There are no restrictions on the use of the drug in children older than 5 years.

    Pregnancy and lactation:

    Reproductive studies in animals showed no risk factor for the fetus. Studies to study the possible effects of the drug on the body of pregnant women and nursing mothers have not been carried out to date.Treatment Solkodermom in relation to this category of patients should be prescribed only in cases where the potential benefit of its use for the mother exceeds the possible risk to the fetus.

    Dosing and Administration:

    For external use only; The procedure should be performed by a doctor or medical personnel under the supervision of a physician.

    Before the procedure, the area of ​​the affected area of ​​the skin is treated with ethyl alcohol or ether. Solkoderm applied directly to the affected area of ​​the skin. To apply the drug to the skin, a special plastic applicator with a sharp and blunt ends is used in each package. A sharp edge is used mainly to apply the drug to small areas of affected skin; The blunt end is used to treat extensive lesions.

    As an alternative method of applying the preparation, the attached glass capillary is used. Combined skin lesions 2-3 cm2 can also be processed with a glass capillary. To fill the preparation with a glass capillary, it must be immersed in Solkoderm solution for several minutes.Care should be taken with the application, avoiding the application of too large volumes of Solcoderm solution and damage to the underlying layers of the tissue. It is necessary to apply as much solution as it absorbs the tissue of the affected area of ​​the skin. Solkoderm is carefully applied to the affected area of ​​the skin with a plastic applicator or glass capillary and then evenly distributed over the surface of the selected area of ​​the skin with light pressure using a plastic applicator until the solution is completely penetrated into the tissue. During the next 3-5 minutes, it is necessary to carefully monitor the changes occurring on the treated area: skin discoloration occurs with the appearance of a characteristic pale gray or yellowish hue. The procedure should be repeated until the above skin color changes occur.

    When treating keratinized warts, the top layer of the stratum corneum should be removed beforehand.

    Affected areas of skin with a diameter of more than 10 mm are processed Solkoderm only if it is determined that only the upper layer of the skin has been pathologically altered.

    In the presence of multiple foci of skin lesions, Solcoderm should be treated in several stages, with an interval of approximately 4 weeks. During each procedure, no more than 2-3 lesions with a total area of ​​no more than 2-3 cm can be treated2.

    During the procedure, a mild transient erythema and the appearance of a white ischemic ring on healthy skin around the site of application of the drug may be observed. These phenomena are considered normal and do not require special treatment. In cases of pain, treatment should be immediately interrupted. Within a few days after the procedure, the treated area of ​​the skin acquires a dark brown hue and dries to form a scab. In case of unsatisfactory mummification of pathologically altered tissue, a repeated procedure can be performed in a few days.

    In order to facilitate fixation and mummification of pathologically altered tissues treated, the affected areas should be treated 2-3 times a day with a pad moistened with 70% alcohol (especially after taking a bath or after washing).

    Side effects:

    Hypersensitivity.Treatment with Solcoderm is often associated with the occurrence of a short-term burning at the site of application, which usually lasts for several minutes. When there is severe local irritation and severe itching in the adjacent areas of the skin, it is recommended to use a cream containing glucocorticosteroids, or an ointment with an anesthetic effect.

    Overdose:

    If not properly applied or overdosed, deep layers of tissue can be damaged.

    An ulcer formed due to an overdose is treated as a normal wound.

    Interaction:

    Interaction Solkoderma with other drugs of local action is not established.

    Special instructions:

    - Do not use Solkoderm on inflamed skin.

    - In cases of pain, treatment should be immediately interrupted.

    - The use of too large doses of Solcoderm can lead to acid burns and damage to deep layers of tissue.

    - Special precautions should be observed when applying Solcoderm solution to the face, especially on the skin areas located near the eyes.

    - If an accidental ingestion of Solcoderm's solution to healthy skin occurred, it should be immediately removed with a cotton swab moistened with water. If an accidental ingestion of Solcoderm solution into the eye occurs, it is necessary to perform an anti-burn therapy. Solkoderm solution drops, fallen on furniture or clothes, must be washed off with water.

    - After a biopsy of the affected area of ​​the skin, it is recommended to wait 8-10 days before starting treatment with Solcoderm solution.

    - Special care is required in the treatment of benign skin tumors treated with Solcoderm, previously treated with other drugs and other methods.

    - Allergic reactions. The use of Solcoderm can lead to a change in the pigmentation of the skin and the formation of scar tissue. However, provided that the healing process proceeds normally, there is no infection, and the resulting scab falls off spontaneously, the risk of such undesirable effects is negligible.

    - Utilization of used ampoules: before discarding the ampoule, the remainder of the solution should be washed off in running water. Empty ampoule can be thrown into a garbage container.

    - Since Solcoderm's solution is chemically unstable after opening the ampoule, a new ampoule must be used for each therapeutic procedure. "

    - Before opening the ampoule, shake and knock down the solution that hit the top of the ampoule. The neck of the ampoule is broken due to the risk. The opened ampoule should be kept strictly vertically by fixing it in a special socket of the outline package for ampoules.

    - Scraping can not be removed by scraping or using mechanical means. The scab should be eliminated spontaneously, otherwise it may damage the processes of tissue healing and the formation of scars.

    - Before the complete healing of the Solkoderm-affected lesion (approximately 2-4 months after the therapy), direct sunlight and ultraviolet radiation should be avoided.

    Form release / dosage:

    Solution for external use.

    Packaging:

    0.2 ml of solution in ampoules of colorless glass with a risk for opening the ampoule.

    1 ampoule complete with a set of plastic applicators (1 pc.) And glass capillaries (2 pcs.) Is placed in a cardboard contour mesh package.

    Contour pack together with instructions for use are put in a cardboard box.

    Storage conditions:

    The drug should be stored at a temperature of 15 to 25 ° C.

    Keep out of the reach of children!

    Handle with care!

    Shelf life:

    2 years. Do not use the medicinal product after the expiration date indicated on the package.

    Terms of leave from pharmacies:On prescription
    Registration number:П N015196 / 01
    Date of registration:21.07.2008
    The owner of the registration certificate:MEDA Pharmaceuticals Switzerland GmbHMEDA Pharmaceuticals Switzerland GmbH Switzerland
    Manufacturer: & nbsp
    Representation: & nbspMEDA Pharmaceuticals Switzerland GmbH MEDA Pharmaceuticals Switzerland GmbH Switzerland
    Information update date: & nbsp10.11.2015
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