Technetium [99mTc] sextibi (Technetium [99mTc] sestamibi)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Diagnostic tools

Included in the formulation
  • Technetril, 99mTc
    lyophilizate in / in 
    DIAMED, LLC     Russia
    • АТХ:

    V.09.G.A   Compounds of technetium 99m

    Pharmacodynamics:

    Does not have a pharmacological effect when used in recommended dosages.

    Pharmacokinetics:

    After intravenous injection quickly leaves the vascular bed, in 3-5 minutes the concentration in the blood plasma is not more than 2%. The maximum concentration in the myocardium is reached after 5 minutes and remains for 3 hours.

    The half-life is 6 hours. Elimination by the kidneys.
    Indications:

    It is used to diagnose blood flow in the myocardium.

    ICD-10

    XXI.Z00-Z13.Z03   Medical surveillance and evaluation in case of suspected disease or pathological condition

    Contraindications:

    Individual intolerance.

    Carefully:

    Childhood.

    Pregnancy and lactation:

    Recommendations for FDA - Category C. Contraindicated in pregnancy and lactation.

    Dosing and Administration:

    Intravenous for 370-1100 MBq 4 hours after eating.

    The highest daily dose: 1100 MBq.

    The highest single dose: 1100 MBq.

    Side effects:

    Nausea, fever, impaired sense of smell, transient leukocytosis.

    Allergic reactions.

    Overdose:

    Arterial hypotension, dyspnea.

    Treatment is symptomatic.

    Interaction:

    When used simultaneously with blockers of slow calcium channels and β-adrenoblockers, it is possible to obtain false negative test results.

    Special instructions:

    The use of the drug is possible only in a specialized hospital.

    Instructions
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