Terpincode® (Terpincodum® )

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceCodeine + Sodium bicarbonate + Terpin hydrateCodeine + Sodium bicarbonate + Terpin hydrate
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  • Terpincode®
    pills inwards 
    PHARMSTANDART-FORESTRY, OJSC     Russia
    • Dosage form: & nbsppills
    Composition:

    Composition per one tablet:

    Active substances: codeine 8 mg, terpinehydrate - 250 mg, sodium hydrogen carbonate - 250 mg.

    Excipients: starch cartofel - 71.1 mg, stearic acid - 5.9 mg, talc - 15 mg.

    Description:

    Tablets of white color, flat-cylindrical with a facet and a risk. Allowed a slight marbling.

    Pharmacotherapeutic group:antitussive combined (anti-cough opioid + expectorant).
    ATX: & nbsp

    R.05.F.A.02   Opium derivatives in combination with expectorants

    Pharmacodynamics:

    Combined drug. Codeine - antitussive drug of central action; alkaloid of the phenanthrene series. The opioid receptor agonist, reduces the excitability of the cough center. In recommended therapeutic doses does not cause depression of the respiratory center, does not disrupt the function of ciliated epithelium and does not reduce bronchial secretion, enhances the action of analgesics, hypnotics and sedatives. Activation of opioid receptors in the intestine causes relaxation of smooth muscles, decreased peristalsis and spasm of all sphincters.

    Terpinhydrate enhances the secretion of bronchial glands, has an expectorant effect.

    Sodium bicarbonate shifts the pH of the bronchial mucus to the alkaline side, reduces the viscosity of the sputum, to some extent also stimulates the motor function of the ciliated epithelium and bronchioles.

    Terpinkod ® weakens the cough reflex and promotes the excretion of mucus from the respiratory tract during coughing. The maximum action occurs 30-60 minutes after ingestion and lasts for 2-6 hours.

    Indications:

    "Dry" cough of different etiology in diseases of the lungs and respiratory tract (including bronchopneumonia, bronchitis, emphysema) in adults and children over 12 years.

    Contraindications:

    Hypersensitivity to the drug components, respiratory failure, bronchial asthma, simultaneous intake of ethanol or narcotic analgesics, children's age (up to 12 years), pregnancy and lactation.

    Carefully:Patients with impaired renal function It is recommended to extend the intervals between methods of the drug.
    Pregnancy and lactation:contraindicated
    Dosing and Administration:

    Inside, 1 tablet 2-3 times a day.The maximum duration of treatment without consulting a doctor is 5 days.

    Side effects:

    Allergic reactions (itching, hives). Nausea, vomiting, constipation, headache, drowsiness. With prolonged uncontrolled application, it is possible to develop dependence on codeine.

    Overdose:

    Symptoms: vomiting, drowsiness, atony of the bladder, impaired coordination of eyeball movements with visual impairment, bradypnoe, respiratory center depression, arrhythmias, bradycardia.

    Treatment: gastric lavage with activated charcoal and potassium permanganate, the introduction of respiratory analeptics, atropine and a competitive physiological antagonist codeine-naloxone.

    Interaction:

    Chloramphenicol inhibits the metabolism of codeine in the liver and thereby enhances its effect. With the simultaneous use of drugs that depress the central nervous system, it is possible to increase the sedative effect and inhibitory effect on the respiratory center. Codeine enhances the effect of ethanol on psychomotor functions.

    When using codeine in large doses, the action of cardiac glycosides (digoxin etc.) can be amplified, tk.in connection with the weakening of peristalsis, their absorption increases. Adsorbents, astringents and enveloping agents can reduce the absorption of codeine.

    Special instructions:

    In patients with impaired renal function withdrawal of codeine is delayed, therefore It is recommended to extend the intervals between methods of the drug.

    During taking the drug, you can notto drink alcohol. Athletes should remember that the drug contains codeine and is doping.

    Effect on the ability to drive transp. cf. and fur:In connection with the possibility of developing sedative action, during the treatment it is not recommended to drive vehicles and engage in other potentially hazardous activities requiring increased concentration of attention, speed of psychomotor and motor reactions.
    Form release / dosage:

    Pills.

    Packaging:For 10 tablets in a planar cell package. 1 package with instructions for medical use in a pack of cardboard.
    Storage conditions:Store at a temperature not exceeding 25 ° C. Keep out of the reach of children.
    Shelf life:4 years. Do not use after the expiration date printed on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:P N001144 / 01
    Date of registration:04.12.2007
    The owner of the registration certificate:PHARMSTANDART-FORESTRY, OJSC PHARMSTANDART-FORESTRY, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp29.05.2012
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