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Dosage form: & nbspLiofilizate for the preparation of a solution for external use.
Composition:The active substance is the enzyme terrylitin, obtained from native solutions of Aspergillus terricola H-20.
Description:The porous mass or powder is white or white with a yellowish brown color, odorless. Hygroscopic.
Pharmacotherapeutic group:Proteolytic agent.
ATX: & nbsp
  • Proteolytic enzymes
  • Pharmacodynamics:Terrylitin® is a proteolytic enzyme, the product of the life of a mold. Its application is based on the ability to break down necrotic tissue, dilute purulent exudate and blood clots.
    Indications:Purulent wounds, burns, trophic ulcers, pressure sores.
    Contraindications:
    Hypersensitivity to the drug, bleeding ulcers and wounds, ulceration of malignant tumors, pregnancy, lactation.
    Simultaneous use of thrombolytic agents.
    Carefully:The location of the main blood vessel in the wound; diseases accompanied by delayed blood clotting.
    Pregnancy and lactation:The use is contraindicated.
    Dosing and Administration:
    Outer in the form of a solution containing in 1 ml 40-50 PE (Proteolytic Units).Before use, the contents of one vial (200 PE) are dissolved in 4-5 ml, or in 2-2.5 ml (100 PE) of purified water, in 0.9% sodium chloride solution or 0.25% novocaine solution.
    The solution is moistened with a sterile napkin, which is applied to the wound and covered with a moisture-proof dressing.
    In the treatment of deep burns and other lesions with a large number of necrotic tissues and for the rejection of the scab, Terrylitin® is used in powder form, dusting the affected surface. A sterile napkin, slightly moistened with 0.9% sodium chloride solution or 0.25% novocaine solution, and a waterproof dressing are applied on top. Change dressings produced after 1-2 days. At the same time, the areas of necrotically altered tissues are removed, the surface is washed with a 3% solution of hydrogen peroxide, dried and again powdered with Terylitin® powder.
    Treatment with Terylitin® continues until complete rejection of necrotic tissues, melting of fibrinous-purulent deposits and the formation of pure, juicy granulations.
    Side effects:Allergic reactions.
    Overdose:Cases of overdose are not described.
    Interaction:
    Terylitin® promotes better penetration into the inflammatory focus of othersmedicines, is compatible with antibiotics: lincomycin, ampiox, streptomycin, ampicillin.
    The drug is compatible with antimicrobial and other chemotherapeutic agents.
    Special instructions:
    When external application of Terrylitin ® is necessary to ensure sufficient drainage of the wound.
    Do not administer intravenously.
    Form release / dosage:
    Liofilizate for solution for external use

    Packaging:
    100 or 200 PE in ampoules or glass bottles. For 10 ampoules (bottles) in
    a box or a pack of cardboard with instructions for use, an ampoule scarifier.
    By 1, 3 or 5 ampoules (bottles) in a contour mesh package with instructions for use by the ampoule scaler in packs or carton boxes.

    Storage conditions:
    In a dry, dark place at a temperature of 0 to 10 ° C.
    Keep out of the reach of children.

    Shelf life:

    3 years. Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-009849/09
    Date of registration:04.12.2009 / 07.05.2014
    The owner of the registration certificate:St. Petersburg Research Institute of Vaccines and Serums and the enterprise for the production of bacterial preparations FSUE FMBASt. Petersburg Research Institute of Vaccines and Serums and the enterprise for the production of bacterial preparations FSUE FMBA
    Manufacturer: & nbsp
    Information update date: & nbsp03.03.2016
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