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Dosage form: & nbspvaginal tablets
Composition:

For 1 tablet:

Active substances:

Ternidazole

0.2 g

Neomycin sulfate

Nystatin

100,000 ME

Prednisolone sodium metasulfobenzoate

0.0047 g,

is equivalent to prednisone

0.003 grams

Excipients:

Wheat starch

0.264 g

Lactose Monohydrate

q.s. up to 1.2 g

Silica colloidal dioxide

0.006 g

Magnesium stearate

0.01 g

Sodium carboxymethyl starch

0.048 g

Description:

Tablets of light yellow color with possible impregnations of more dark or light shades, flat, oblong, with a facet along the edges and with a "T" on both sides.

Pharmacotherapeutic group:antimicrobial agent combined (antibiotic-aminoglycoside + antimicrobial and antiprotozoal means + antifungal agent + glucocorticosteroid)
ATX: & nbsp
  • Antibiotics in combination with corticosteroids
  • Pharmacodynamics:

    Combination drug for topical application in gynecology. Has antimicrobial, anti-inflammatory, antiprotozoal, antifungal action; ensures the integrity of the mucous membrane of the vagina and the constancy of the pH.

    Ternidazole - antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (an integral part of the cell membrane), changes the structure and properties of the cell membrane.Has a trichomonocidal effect, is also active against anaerobic bacteria, in particular, gardnerella.

    Neomycin - a broad-spectrum antibiotic from the aminoglycoside group. It is bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; in a relationship Streptococcus spp., is inactive.

    The stability of microorganisms develops slowly and to a small extent.

    Nystatin - Antifungal antibiotic from the group of polyenes, highly effective inyeastbfungi of the genus Candida, changet nknapsacksaemostoof the membranes and slows their growth.

    Prednisolone - dehydrogenated analog of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exsudative action.

    Indications:

    Treatment of vaginitis caused by microorganisms sensitive to the drug, including:

    - bacterial vaginitis;

    - trichomoniasis of the vagina;

    - vaginitis caused by fungi of the genus Candida;

    - mixed vaginitis.

    Prevention of urogenital infections / vaginitis, including:

    - before gynecological operations;

    - before childbirth and abortion;

    - before and after installation of intrauterine devices;

    - before and after diathermocoagulation of the cervix;

    - before hysterography.

    Contraindications:

    Hypersensitivity to any component of the drug.

    Pregnancy and lactation:

    It is possible to use the drug from the second trimester of pregnancy. The use of the drug in the first trimester of pregnancy and during lactation is possible only in cases where the potential benefit to the mother exceeds the risk for the fetus or baby.

    Dosing and Administration:

    For vaginal application.

    One tablet is injected deep into the vagina in the "lying" position before going to sleep. Before entering the vagina, the tablet should be held in water for 20-30 seconds. After the introduction, lie down for 10-15 minutes.

    The average duration of the therapeutic course of therapy is 10 days; in the case of confirmed mycosis may be increased to 20 days; the average duration of the preventive course is 6 days.

    Side effects:

    A burning sensation, itching and irritation in the vagina (especially at the beginning of the treatment).

    In some cases, allergic reactions are possible.

    Overdose:

    No data on overdose cases.

    Interaction:

    Not found.

    Special instructions:

    In the case of treatment of vaginitis, trichomoniasis, simultaneous treatment of sexual partners is recommended.

    Do not stop treatment during menstruation.

    Form release / dosage:

    Tablets are vaginal.

    Packaging:For 6 or 10 tablets per strip (aluminum foil), one strip with instructions for use is packed in a cardboard box.
    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:On prescription
    Registration number:П N015129 / 01
    Date of registration:21.07.2008 / 26.05.2015
    The owner of the registration certificate:Bouchard-Recordati LaboratoriesBouchard-Recordati Laboratories France
    Manufacturer: & nbsp
    Representation: & nbspRUSFIK LLC RUSFIK LLC Russia
    Information update date: & nbsp23.02.2016
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