Pumpkin seed oil (Oleum seminum Cucurbitae)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Hepatoprotectors

Regenerants and reparants

Included in the formulation
  • Pepon®
    capsules inwards 
    Teva Pharmaceutical Enterprises Co., Ltd.     Israel
  • Tykveol®
    butter inwards 
    NGO EUROPA-BIOFARM, CJSC     Russia
    • АТХ:

    A.05.B.A   Preparations for the treatment of liver diseases

    Pharmacodynamics:

    Has a pronounced antioxidant effect, due to inhibition of lipid peroxidation in biological membranes. Contains essential phospholipids, which contribute to the restoration of the cell membrane of hepatocytes, its structure and function. Regulates the exchange of cholesterol and triglycerides, is involved in the metabolism of arachidonic acid. Has anti-inflammatory and cytoprotective effects when applied topically. Normalizes the functional state of the biliary tract, regulating the chemical composition of bile. It has antiandrogenic properties, reducing the proliferation of prostate cells, normalizing its function by improving microcirculation and anti-inflammatory action.

    Pharmacokinetics:

    Not studied.

    Indications:

    For oral administration:

    - cirrhosis of the liver;

    - chronic hepatitis;

    - fatty liver degeneration;

    - infectious hepatitis;

    - toxic liver damage (drugs, industrial poisons, alcohol);

    - cholecystitis (non-calculous);

    - cholestasis;

    - biliary dyskinesia;

    - gastritis;

    - colitis, enterocolitis (non-infectious genesis);

    - hemorrhoids;

    - Atherosclerosis;

    - prostatitis;

    benign prostatic hyperplasia.

    For rectal administration:

    - chronic prostatitis;

    - benign prostatic hyperplasia of the I-II stage with concomitant prostatitis.

    For external and local use:

    herpes;

    - dermatitis;

    - psoriasis;

    - eczema;

    - Burns and burn disease;

    - cervical erosion;

    - Colpitis, endocervicitis;

    - Periodontal disease.

    ICD-10

    I.A50-A64.A60   Anogenital herpetic viral infection [herpes simplex]

    I.B00-B09.B00   Infections caused by the herpes simplex virus [herpes simplex]

    I.B15-B19.B15   Acute hepatitis A

    I.B15-B19.B16   Acute hepatitis B

    I.B15-B19.B17.1   Acute hepatitis C

    I.B15-B19.B18.9   Chronic viral hepatitis, unspecified

    IX.I70-I79.I70   Atherosclerosis

    IX.I80-I89.I84   Hemorrhoids

    XI.K00-K14.K05   Gingivitis and periodontal disease

    XI.K20-K31.K29   Gastritis and duodenitis

    XI.K50-K52.K50.9   Crohn's disease, unspecified

    XI.K50-K52.K51   Ulcerative colitis

    XI.K70-K77.K70   Alcoholic liver disease

    XI.K70-K77.K71   Toxic liver disease

    XI.K70-K77.K73.9   Chronic hepatitis, unspecified

    XI.K70-K77.K74   Fibrosis and cirrhosis of the liver

    XI.K80-K87.K81.0   Acute cholecystitis

    XI.K80-K87.K82.8   Other specified diseases of the gallbladder

    XII.L20-L30.L20.8   Other atopic dermatitis

    XII.L40-L45.L40   Psoriasis

    XIV.N40-N51.N40   Hyperplasia of the prostate

    XIV.N40-N51.N41.8   Other inflammatory diseases of the prostate

    XIV.N70-N77.N72   Inflammatory disease of the cervix

    XIV.N80-N98.N86   Erosion and ectropion of the cervix

    XIX.T20-T32.T30   Thermal and chemical burns, unspecified

    Contraindications:

    Hypersensitivity to the drug, children's age, pregnancy.

    Carefully:Hypersensitivity.
    Pregnancy and lactation:

    Controlled trials in humans have not been carried out. There is no information on the penetration of human milk. Do not apply!

    Category of recommendations for FDA is not defined.

    Dosing and Administration:

    Inside prescribe the drug 30 minutes before eating 1 teaspoon of oil 3-4 times a day for 1-3 months or 4 capsules 3 times a day during or after a meal.

    With external and local application smeared affected areas 2-3 times a day.

    With hemorrhoids and prostatitis (along with oral administration), microclysters are prescribed 2 times a day.

    With periodontal disease, local application of the drug is prescribed.

    In gynecological practice, vaginal tampons impregnated with a drug in a dose of 10 ml are used.

    Rectal suppositories Enter into the rectum (previously moistened with water) 1 suppository 1-3 times a day. The course of treatment is from 10 days to 3 months, or spend short courses of treatment for 10-15 days for 6 months.

    Side effects:

    From the side digestive system: rarely - indigestion, diarrhea.

    In rare cases, possible allergic reactions.

    Overdose:

    No data.

    Interaction:

    Not studied

    Special instructions:

    The drug is used in the form of monotherapy, as well as in the complex therapy.

    The drug is compatible with any food.

    In inflammatory and degenerative processes of the upper gastrointestinal mucosa recommended to take the drug in the form of oil, should avoid taking the drug in the form of capsules.

    Instructions
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