Fluorinated glucocorticosteroid drug, has a pronounced anti-inflammatory, antiallergic and antiexudative action.
Interacting with a specific protein receptor in target tissues, regulates the expression of cortico-dependent genes and thus affects protein synthesis.Reduces the formation, release and activity of inflammatory mediators (histamine, kinin, prostaglandins, lysosomal enzymes). Suppresses the migration of cells to the site of inflammation; reduces vasodilation and increased vascular permeability in the focus of inflammation. Stabilizes lysosomal enzymes of leukocyte membranes; Suppresses the synthesis of antibodies and disrupts the recognition of the antigen. It inhibits the release of interleukin 1, interleukin 2, gamma-interferon from lymphocytes and macrophages. It induces the formation of lipocortin, inhibits the release of eosinophils by inflammatory mediators and stabilizes the membranes of mast cells. All these effects are involved in suppressing the inflammatory response in tissues in response to mechanical, chemical or immune damage.