Intravenously drip with a speed in adults 30 cap / min, in children 40-50 cap / min. The contents of one ampoule are dissolved in 200 ml of 0.9% sodium chloride solution. Do not exceed the indicated rate of administration.The drug is used in a hospital.
The following dosages are recommended:
- oncological patients in the period of preoperative preparation of Ceruloplasmin are administered in a dose of 1.5-2.0 mg / kg of body weight per day; course of treatment 7-10 intravenous administrations, daily or every other day, depending on the patient's condition;
- in the postoperative period, a single dose is determined by the amount of blood loss and is from 1.5 mg / kg with moderate blood loss, up to 6 mg / kg in case of massive blood loss. The course of treatment consists of daily (once a day) intravenous injections for 7-10 days;
When conducting radio and chemotherapy, a single dose is 4-6 mg / kg of body weight, the course of treatment consists of 10-14 intravenous administrations (3 injections per week). For patients with hemoblastoses, the single dose is 1.5-3.0 mg / kg, the course of treatment is 7-10 intravenous infusions, prescribed daily 1 time per day; in acute osteomyelitis, a single dose of 2.5 mg / kg of body weight, the course of treatment consists of 5 intravenous administrations, administered daily or every other day. In chronic osteomyelitis, Ceruloplasmin is administered at 5 mg / kg 2-3 times at intervals of 1-2 days, and then 3-7 injections of 2.5 mg / kg are given.
In pediatric practice, the following dosages are recommended:
- children from 6 months to 1 year - 50 mg (100 ml of solution);
- from 1 year to 12 years - 100 mg;
- from 13 to 18 years - 200 mg.
For the prevention and / or treatment of posthemorrhagic anemia in surgical operations in children, Ceruloplasmin is administered within 2 days prior to surgery, intraoperatively and within 2-10 days after surgery.
For the prevention and / or treatment of anemia in children with purulent-surgical diseases, Ceruloplasmin is administered for 7-10 days daily on the days of antibiotic therapy.
In children with oncological diseases for the prevention and / or treatment of radiation anemia with radiation therapy, Ceruloplasmin is administered once a week throughout the course of radiotherapy; for the prevention and / or treatment of toxic anemia Ceruloplasmin is administered on chemotherapy days throughout the course; To prevent and treat toxic and radiation anemia on the background of chemoradiotherapy, Ceruloplasmin is administered once a week on the day of chemotherapy throughout the course of treatment.