Included in the formulation
АТХ:D.10.A.X.30 Other drugs for topical treatment of acne in various combinations
Pharmacodynamics:Stimulator of tissue repair. When the hyaluronic acid interacts with water molecules, a dispersion matrix arises, replenishing the missing cellular tissue. It forms a natural supporting framework for cells involved in wound healing, increases the activity of granulocytes and macrophages, enhances fibroblast proliferation and angiogenesis.
Compared with sodium hyaluronate, zinc hyaluronate has a bacteriostatic effect against many bacteria.
Affects all 3 phases of the wound process; highly effective in chronic ulcers of the shin (contributes to epithelization of the ulcer defect, faster and uniform healing, normalizes the condition of surrounding tissues). Reduction of the pain syndrome is noted on the 2-3rd day of treatment, disappearance - on the 9-10th day. Reduces tenderness when dressing (prevents the drying of the bandage).
Pharmacokinetics:When topical application is practically not absorbed, a small amount of the drug is detected in the plasma.
Indications:Solution: poorly healed, infected wounds, trophic ulcers, shin ulcers, bedsores, fistulas, acceleration of normal wound healing.
Gel: all types of light and moderate acne (including comedones and papulo- pustular acne).
XII.L80-L99.L97 Ulcer of lower limb, not elsewhere classified
XII.L80-L99.L89 Decubital ulcer
XII.L60-L75.L70 Acne
XIX.T08-T14.T14.1 Open wound of unspecified area of the body
XII.L00-L08.L08.9 Local infection of skin and subcutaneous tissue, unspecified
XIX.T79.T79.3 Post-traumatic wound infection, not elsewhere classified
Contraindications:The period of breastfeeding; hypersensitivity to any of the components of the drug.
Pregnancy and lactation:Category of recommendations for FDA is not defined. Adequate and well-controlled studies on humans and animals have not been conducted. The use of the drug in pregnancy is possible only in cases where the intended benefit to the mother exceeds the potential risk to the fetus.
If you need to use the drug during lactation, you should decide whether to stop breastfeeding (due to lack of experience).
Dosing and Administration:Locally. Solution: after washing the wound with a 3% solution of hydrogen peroxide or saline solution directly onto the wound surface. Possible closing with a gauze cloth of the appropriate size. The dressing should be changed 1-2 times a day.
Gel: evenly applied to thoroughly cleaned skin with a thin layer 2 times a day.
Side effects:Burning sensation in the place of application (at the beginning of treatment); sensation of constriction of the skin and hyperemia of the skin (with the use of gel).
Very rarely in the adjoining areas of the skin, allergic reactions (irritation and contact dermatitis) are possible.
Interaction:There are no data on the interaction of zinc hyaluronate with other drugs.
Special instructions:After opening the vial, the solution should be used within 4 weeks.
Does not have photosensitizing properties, does not stain skin and linen.