The need to actualize instructions for the use of appropriate drugs has been identified.
For preparations containing as an active substance vancomycin in the section "Indication for use" it is necessary to additionally indicate: "For oral administration: pseudomembranous colitis caused by Clostridium difficile; enterocolitis caused by Staphylococcus aureus", and in the section "Method of administration and dosage" indicate dosing regimens for these conditions: "Vancomycin can be used orally for the treatment of pseudomembranous colitis caused by Clostridium difficile, due to the use of antibiotics, as well as for the treatment of staphylococcal enterocolitis. Intravenous administration of the drug has no advantages for the treatment of these diseases. The drug should be used in the following doses: adults 0.5-2 g 3-4 times / day, children 0.04 g / kg 3-4 times / day. The total daily dose should not exceed 2 g.The appropriate dose is prepared in 30 ml of water and given to the patient to drink or injected through the probe. To improve the taste of the solution, ordinary food syrups can be added to it. Duration of treatment is from 7 to 10 days. Vancomycin Ineffective in ingestion in case of other types of infections. ".
The dosage form for these drugs should be defined as "powder / lyophilizate for the preparation of a solution for infusion and oral administration".