The drug is taken internally.
Preparation of the patient
1. The patient should not eat for 6 hours before the test. Immediately before the test should not smoke.
2. 30 days before the test, antibiotics and bismuth preparations are excluded.
3. For 14 days before the test, treatment with radiopharmaceuticals and / or proton pump inhibitors is excluded, as well as the administration of sucralfates.
4. The test is recommended before the endoscopy of the digestive tract.
Dosage and test procedure
The injected single dose of the drug for diagnosis - 1 capsule, activity 37 kBq.
During the test, the patient is sitting. The patient takes a capsule and drinks 20 ml of warm water. After 3 minutes the patient also drinks 10 ml of warm water. At 10 minutes after taking the capsule, the patient takes a deep breath and after 5-10 seconds of breath holding slowly exhales air with a plastic tube into the blue absorbing liquid that is in the scintillation vial. When the blue color of the absorbing liquid is discolored, the patient stops exhaling. After this, 7.5 ml of scintillation solution is added to this flask and the radioactivity of the sample is measured on a beta counter.
Interpretation of results
The test is considered positive, if the radioactivity of the sample exceeds 200 decays per minute (rpm, DPM), negative - the radioactivity of the sample is less than 50. The result of 50 to 200 - is considered uncertain and requires (if necessary) a re-examination. Re-examination is possible in 24 hours.
A false negative result is possible if:
- antibiotics and / or bismuth preparations were taken less than 30 days before the test;
- proton pump inhibitors were taken less than 14 days before the test;
- sucralfates were taken less than 14 days before the test;
- there were difficulties with swallowing the capsule (a possible way out was to collect an additional portion of air for 15-20 minutes);
- the patient took food less than 6 hours before the test.
A false positive result is possible if:
- after resection of the stomach followed by a rapid growth of bacteria that do not release Hp-urease;
- with achlorhydria;
- for the chemiluminescence of the sample.
If the sample count was carried out immediately after the addition of the scintillacin liquid and the count values are in the range of 50-300 r / min, it is recommended to repeat the sample count after 1-2 hours or the next day.
Radiation loads on the patient's organs when using a radiopharmaceutical "Ureacaps, 14FROM"
Fat layer | 0,198 |
Bones | 0,810 |
Lungs | 0,027 |
Gonads | 0,016 |
Bladder | 0,315 |
The critical organ for radiation exposure is the bladder.