Uriflorin - instructions for use, dose, side effects, contraindications

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Dosage form: & nbsppills

Composition:

Bearberry leaves - 0.3 g

Auxiliary substances:

Milk sugar - 0.13 grams

Potato starch - 0.03 g

Microcrystalline cellulose (for medical purposes) - 0.07 g

Polyvinylpyrrolidone is a medium molecular weight medical - 0.025 g

Calcium stearate - 0.005 g - until tablets weighing 0.56 g

Description:

: tablets from light green to dark green color, with white and brown impregnations, flat-cylindrical shape with a facet and a risk.

Pharmacotherapeutic group:Diuretic agent of plant origin.

Pharmacodynamics:

The drug has a diuretic, anti-inflammatory and antiseptic effect.

Diuretic and uroantiseptic properties of bearberry leaves are associated with phenolic glycosides arbutin and methylarbutine, as well as with hydroquinone and its methyl ester, which have antimicrobial and locally irritating effects. Flavonoids of leaves

bearberry intensify diuresis, which leads to an intensive elimination of sodium and chlorine ions from the body.

Antimicrobial activity is due to tannins and phenolic glycosides. The antimicrobial effect of tannins is based on their ability to form complex compounds with proteins of microorganisms.

Pharmacokinetics:

The drug contains a complex of biologically active substances, the main of which is arbutin. Arbutin is quickly absorbed when taken orally. Splitting arbutin with the formation of free hydroquinone occurs under the influence of enzymes of the intestinal microflora, in particular E. coli. After absorption in the intestine hydroquinone is metabolized in the liver, where conjugates with glucuronic and sulfuric acids form. Glucuronide and hydroquinone sulfate are intensively excreted in the urine after several hours. The greatest excretion is observed in the first 6 hours. 70-75% of the dose is allocated after 24 hours.

Indications:

In the complex therapy of inflammatory diseases of the urinary bladder and urinary tract (cystitis, urethritis).

Contraindications:

Hypersensitivity to the components of the drug, acute renal and hepatic insufficiency, acute glomerulonephritis; deficiency of lactase, lactose intolerance, glucose-galactose malabsorption; children's age till 18 years.

Carefully:

With glomerulonephritis (there may be irritation of the renal parenchyma).

Pregnancy and lactation:

, The use of the drug is contraindicated in pregnancy and during the period -

breastfeeding. ' ' - . .

Dosing and Administration:

Inside. 1 tablet 3-4 times a day after 30 - 40 minutes after eating.

The course of treatment is 20 - 25 days; if necessary, the treatment is repeated after 10-12 days (no more than 4 courses per year).

Side effects:

Allergic reactions are possible; nausea, vomiting, diarrhea.

With prolonged use of the drug (more than 1 month), there may be an exacerbation of inflammatory phenomena in the urinary system as a result of prolonged irritation of the renal tubules.

Overdose:

To date, cases of overdose with the use of the drug has not been recorded. When taking the drug in doses exceeding the recommended dose, it is possible to increase dose-related side effects. Treatment: symptomatic.

Interaction:not found

Special instructions:

When taking the drug, urine is colored in a dark green color.

The use of the drug does not affect the performance of potentially hazardous activities requiring special attention and rapid reactions.

Form release / dosage:Tablets 300 mg

Packaging:

For 10 tablets in a planar cell package.

One or two contour squares, together with instructions for use, are placed in a cardboard pack.

For 30 tablets in cans of orange glass, ukuporennyh caps aluminum with perforation.

For 30 tablets in cans of polymeric with a polymeric lid or in cans of polymeric with a shock absorber and a lid pulled with the control of the first opening.

Each bank along with the instruction for use is placed in a cardboard pack.

Storage conditions:

In a dry, dark place at a temperature of not more than 25 ° C.

Keep out of the reach of children place.

Shelf life:

4 of the year.

Do not apply at the end of the period shelf life.

Terms of leave from pharmacies:On prescription

Registration number:LS-000107

Date of registration:18.03.2010

The owner of the registration certificate:MOSCOW PHARMACEUTICAL FACTORY, CJSC MOSCOW PHARMACEUTICAL FACTORY, CJSC Russia

Manufacturer: & nbsp

MOSCOW PHARMACEUTICAL FACTORY, CJSC Russia

Representation: & nbspMOSCOW PHARMACEUTICAL FACTORY MOSCOW PHARMACEUTICAL FACTORY Russia

Information update date: & nbsp14.09.2015

Illustrated instructions

Instructions

Uriflorin® (Uriflorin®)