Vaccine for the treatment of staphylo-prosthetic-pseudomonas aeruginosa infections (Vaccine for the treatment of staphylo-prosthetic-pseudomonas aeruginosa infections)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Vaccines, serums, phages and toxoids

Included in the formulation
  • SPCA-vaccine® Staphylo-Protein-Pseudomonas aeruginous adsorbed vaccine
    PC 
    MICROGEN FGUP Scientific and Production Association     Russia
    • АТХ:

    J.07.A.X   Other vaccines for the prevention of bacterial infections

    Pharmacodynamics:

    It causes the formation of antibodies against staphylococci, Proteus and Pseudomonas aeruginosa, accelerates the phagocytic function of neutrophils.

    Pharmacokinetics:

    Not described.

    Indications:

    It is used to prevent purulent-septic complications.

    ICD-10

    I.A30-A49.A49   Bacterial infection of unspecified site

    I.A30-A49.A49.0   Staphylococcal infection, unspecified

    I.B99   Other infectious diseases

    XXI.Z20-Z29.Z29.1   Prophylactic immunotherapy

    Contraindications:

    Age to 18 years, pregnancy and lactation, individual intolerance.

    Carefully:

    History of hypersensitivity to the introduction of vaccines.

    Pregnancy and lactation:

    Recommendations for FDA - Category C. Contraindicated in pregnancy and lactation.

    Dosing and Administration:

    Subcutaneously once in an amount of 0.5 ml with isolated injuries and closed fractures.

    In case of extensive injuries and before routine surgical interventions - three times: 0.5 ml - as a primary dose, then twice in 1 ml with an interval of 14-20 days.

    The highest daily dose: 1 ml.

    The highest single dose: 1 ml.

    Side effects:

    Systemic reactions: hyperthermia, weakness.

    Local reactions: pain and hyperemia at the injection site.

    Allergic reactions.

    Overdose:

    Cases of overdose are not described.

    Treatment is symptomatic.

    Interaction:

    It is not recommended simultaneous administration of the drug with antistaphylococcal immunoglobulin and antistaphylococcal plasma due to the phenomenon of mutual neutralization.

    Special instructions:

    Conducting a specific vaccination is not the reason for the cancellation of treatment with other drugs: antibacterial, anti-inflammatory and other.

    Instructions
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