Included in the formulation
Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):VED
АТХ:J.07 Vaccines
J.07.C.A Combination of vaccines for the prevention of viral and bacterial infections
Pharmacodynamics:Adsorbed vaccine for the prevention of diphtheria, tetanus, pertussis and poliomyelitis. The vaccine is made from diphtheria and tetanus toxins (inactivated and purified), pertussis (subjected to thermal inactivation) and 3 types of poliovirus, prepared on the culture of VERO cells and formalin-inactivated. Forms specific immunity to diphtheria and tetanus toxins, pertussis and polioviruses.
Pharmacokinetics:Immunity is acquired after the second injection of the vaccine, increases with the subsequent vaccine and lasts at least 5 years. Seroconversion to diphtheria toxin is observed in 92-100% of vaccinated, to tetanus toxin - in 100%, to pertussis toxin - in 93% and to poliovirus - in 100%.
Indications:Combined prophylaxis of diphtheria, tetanus, pertussis and poliomyelitis in children aged 2 months to 6 years.
XXI.Z20-Z29.Z27.3 The need for immunization against diphtheria-tetanus-pertussis and poliomyelitis
Contraindications:Hypersensitivity, including for the previous administration of a vaccine containing a pertussis component: a rise in temperature to 40 ° C or higher, a prolonged crying syndrome, convulsions, a shock (if these reactions occurred within 48 hours after the administration of the vaccine). Progressive encephalopathy, accompanied by cramps or without.
Carefully:Vaccination should be delayed in cases of the active phase of any disease, especially infectious. It should be administered with caution in case of streptomycin allergy.
Pregnancy and lactation:No data. The drug is for use in children.
Dosing and Administration:Subcutaneously or intramuscularly (before usem should be shaken thoroughly) according to the following scheme:
1) primary vaccination, consisting of three injections - 0.5 ml at intervals of 1 month;
2) revaccination - 0.5 ml 1 year after the third injection of primary vaccination.
When carrying out mass vaccinations, the vaccine can be administered with a needleless IMOJET injector.
Side effects:Possible short-term (24-48 h) increase in body temperature, local reactions - soreness,compaction and redness of the skin at the injection site.
Special instructions:The presence in the anamnesis of seizures not associated with the previous administration of the vaccine is not a contraindication to its use (if the patient does not have progressive encephalopathy); when vaccinating such patients, prophylactic administration of anticonvulsants and / or antipyretics may be useful.