Included in the formulation
Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):VED
АТХ:J.07.B.B.02 Influenza virus - purified antigen
J.07.B Vaccines for the prevention of viral infections
Pharmacodynamics:Vaccine for the prevention of influenza. The vaccine forms a high specific immunity against influenza and is well tolerated by children and adults. After vaccination, the antibodies appear after 8-12 days, the immunity persists to 12 months, including in the elderly. Protective titers of antibodies to influenza viruses after vaccination of persons of different ages are determined in 75-92% of vaccinated.
Inclusion in the preparation of immunomodulator polyoxidonium provides an increase in immunogenicity and stability of antigens, allows to increase immunological memory, significantly reduce the vaccine dose of antigens, increase the resistance of the organism to other infections due to correction of the immune status.
Pharmacokinetics:No data.
Indications:Active prophylactic immunization against influenza in children from 6 months of age, adolescents and adults without age restriction:
- persons over 60 years of age;
- persons suffering from chronic physical illnesses;
- often suffering from acute respiratory diseases;
- children of preschool age;
- pupils;
- medical workers;
- workers in the service sector, transport, educational institutions, servicemen.
X.J10-J18.J10 Influenza caused by an identified influenza virus
Contraindications:Allergic reactions to previous vaccinations, chicken protein and vaccine components; acute febrile conditions or exacerbation of a chronic disease.
At mild acute respiratory viral infections, acute intestinal diseases vaccination is carried out after the normalization of temperature.
Carefully:Children aged 6 months to 3 years vaccination is carried out at a dose of 0.25 ml twice with an interval between injections of 4 weeks; or in a dose of 0.5 ml once, if the child was vaccinated against the flu in the previous season.
Children over 3 years and adults without age restriction 0.5 ml once.
Pregnancy and lactation:The decision on vaccination of pregnant women should be taken by a doctor individually, taking into account the risk of infection with influenza and possible complications of influenza infection. The vaccination is most safe in the II and III trimesters.
AT experimental research it was found that the vaccine does not have embryotoxic and teratogenic effects.
Breastfeeding is not a contraindication for vaccination.
Dosing and Administration:Vaccination is carried out annually in the autumn-winter period. It is possible to vaccinate at the beginning of an epidemic rise in the incidence of influenza.
Children aged 6 months to 3 years vaccination is carried out at a dose of 0.25 ml twice with an interval between injections of 4 weeks; or in a dose of 0.5 ml once, if the child was vaccinated against the flu in the previous season.
Children over 3 years and adults without age restriction 0.5 ml once.
Patients with immunodeficiency it is possible to administer the vaccine twice in 0.5 ml with an interval between injections of 4 weeks.
The vaccine is injected intramuscularly or deeply subcutaneously into the upper third of the outer surface of the shoulder (in the deltoid muscle), to young children in the anterior anterior surface of the thigh.
Opening of ampoules and the vaccination procedure are carried out with strict adherence to aseptic and antiseptic rules. The drug in the opened ampoule is not subject to storage.
Side effects:Local reactions: very rarely - soreness, swelling and redness of the skin.
Systemic reactions: extremely rare - malaise, headache, weakness, low-grade fever (passing alone 1-2 days later); in extremely rare cases - allergic reactions (with high individual sensitivity).
Overdose:There is no evidence of an overdose of the vaccine.
Interaction:The vaccine can be administered against the background of basic therapy of the underlying disease.
Vaccination of patients receiving immunosuppressive therapy may be less effective.
The vaccine can be used concomitantly with other inactivated vaccines.This should take into account contraindications to each of the vaccines used, the drugs must be injected into different parts of the body with different syringes.
Special instructions:The drug can not be administered intravenously.
In the offices where the vaccination is carried out, it is necessary to have medicines for anti-shock measures and relief of anaphylactic reaction. The vaccinated should be under medical supervision within 30 minutes after the introduction of the vaccine.
On the day of administration of the drug, the vaccinated should be examined by a physician with mandatory thermometry. At a temperature above 37.0 ° C, vaccination is not carried out.
It should be borne in mind that the preparation is not suitable for use in ampoules with broken integrity or marking, with changing physical properties (color, transparency), expired shelf life, violation of requirements for storage conditions.