Vaccine for the prevention of measles and mumps (Vaccinum ad prophylaxim morbillorum, parotitidis)

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
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Clinical and pharmacological group: & nbsp

Vaccines, serums, phages and toxoids

Included in the formulation
  • Vaccine parotitic-measles alive live
    lyophilizate PC 
    MICROGEN FGUP Scientific and Production Association     Russia
    • Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):

    VED

    АТХ:

    J.07.B.D   Vaccine for measles prevention

    J.07.B.D.51   The measles virus in combination with the mumps virus is a live attenuated

    Pharmacodynamics:

    It causes the formation of immunity against the measles virus, mumps.

    Stimulates the production of antibodies to measles and mumps virus, reaching a maximum level of 3-4 weeks and 6-7 weeks after vaccination, respectively.

    Pharmacokinetics:

    No data.

    Indications:

    Scheduled and emergency prevention of measles and mumps.

    ICD-10

    I.B00-B09.B05   Measles

    I.B25-B34.B26   Parotitis

    XXI.Z20-Z29.Z27.8   The need for immunization against other combinations of infectious diseases

    Contraindications:

    Hypersensitivity (including to aminoglycosides, quail egg protein), a pronounced reaction or complication to the previous dose, primary immunodeficiency states, malignant blood diseases, neoplasms, pregnancy.

    Carefully:

    Vaccination can be carried out at the end of acute manifestations of infectious and non-infectious diseases,exacerbations of chronic diseases; after normalization of body temperature for moderate forms ARVI or acute intestinal diseases; 3-6 months after immunosuppressive therapy. After the administration of human immunoglobulin preparations, inoculations against measles and mumps are carried out not earlier than in 2 months. After the introduction of mumps-measles vaccine, immunoglobulin preparations are administered no earlier than 2 weeks. If immunoglobulin is required before this time, vaccination against measles and mumps should be repeated.

    Pregnancy and lactation:

    Contraindicated in pregnancy.

    Dosing and Administration:

    Subcutaneously, immediately before use, mix the vaccine with the solvent (0.5 ml of solvent per 1 vaccine dose of vaccine), inject 0.5 ml under the scapula or into the shoulder region (at the border between the lower and middle third of the shoulder from the outside). Routine vaccinations are carried out twice at the age of 12 months and 6 years for children who do not have measles and mumps.

    Emergency prevention is provided to children aged 12 months, adolescents and adults who have contact with sick measles or mumps,not infected with these infections and not vaccinated against them in accordance with the vaccination calendar (the vaccine is administered no later than 72 hours after contact with the patient).

    Side effects:

    From 4 to 18 days after the introduction of the vaccine: hyperthermia (with mass vaccination, body temperature increase above 38.5 °C should not be more than 2% of vaccinated children), catarrhal phenomena (hyperemia of throat, rhinitis), lasting 1-3 days; rarely - a short-term (2-3 days) insignificant increase in parotid salivary glands (the general condition is not violated at the same time), malaise, korepodobnaya rash.

    Local reactions: insignificant hyperemia of the skin and edema of soft tissues that pass through 1-3 days without treatment.

    Rarely - allergic reactions (in the first 24-48 hours), 2-4 weeks after vaccination - benign serocious meningitis (each case of serous meningitis requires differential diagnosis).

    Overdose:

    No data.

    Interaction:

    Vaccination can be performed simultaneously (on the same day) with other calendar vaccinations (against polio, hepatitis B, pertussis, diphtheria, tetanus) or not earlier than 1 month after the previous vaccination; after the introduction of human Ig - no earlier than 2 months,and after vaccination with mumps vaccine, Ig administration is allowed only after 2 weeks. If Ig is needed before this time, vaccination against mumps and measles should be repeated.

    Special instructions:

    HIV infection is not a contraindication for vaccination.

    With moderate forms of acute respiratory viral infection, acute intestinal diseases, vaccination is carried out immediately after the normalization of body temperature.

    Vaccination is not recommended during the period of rising incidence of serous meningitis.

    Vaccination is performed no earlier than 3-6 months after the end of immunosuppressive therapy.

    Persons temporarily released from vaccination should be monitored and vaccinated after withdrawal of contraindications.

    Febrile convulsions in the anamnesis, as well as hyperthermia over 38.5 °C in the post-vaccination period are an indication for the appointment of antipyretic drugs.

    Immediately prior to the introduction, the vaccine is diluted with diluent for measles, mumps and mumps in live culture dry live vaccines at a rate of 0.5 ml of solvent per vaccination dose of the vaccine. The vaccine should completely dissolve within 3 minutes.

    Vaccine or solvent in ampoules with broken integrity, marking, as well as changing their physical properties (color and transparency), expired or incorrectly stored, are not suitable for use.

    Opening of ampoules and the vaccination procedure are carried out with strict adherence to aseptic and antiseptic rules.

    Ampoules with vaccine and solvent at the incision site are treated with 70% ethanol and break off, while preventing the ingress of ethanol into the ampoule.

    To dilute the vaccine, take all the necessary volume of the solvent and transfer it to an ampoule with a dry vaccine. After mixing, the vaccine is taken up by another needle in a sterile syringe and used for vaccination.

    The dissolved vaccine is used immediately and is not subject to storage.

    Vaccination is recorded in the prescribed registration forms with the name of the drug, the date of vaccination, dose, manufacturer, serial number, date of manufacture, expiration date, response to vaccination.

    Instructions
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