Included in the formulation
Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):VED
АТХ:J.07.B.B Vaccine for the prevention of influenza
J.07.B.01.01 Influenza virus - inactivated whole virus
Pharmacodynamics:Vaccine influenza, inactivated, subunit, adsorbed is a surface glycoproteins (hemagglutinin and neuraminidase) isolated from purified virions of the avian influenza virus type A serotype H5N1 grown on chick embryos sorbed on aluminum hydroxide.
The vaccine causes the formation of specific immunity in humans against avian influenza.
After the second vaccination on days 21-28, the vaccine should cause an increase in homologous antibodies in the sera 4 or more times at least 50% of the vaccinated.
Pharmacokinetics:No data.
Indications:Specific prevention of avian influenza in people aged 18-60 years according to epidemic indications.
XXI.Z20-Z29.Z25.1 The need for immunization against influenza
Contraindications:- aboutacute infectious and non-infectious diseases, chronic diseases in the acute stage - vaccinations are carried out not earlier than a month after recovery (remission).For non-severe acute respiratory viral infections, acute intestinal diseases, vaccination is carried out after normalizing the temperature;
- Hypersensitivity to chicken protein;
- systemic connective tissue diseases;
- adrenal gland diseases;
- hereditary, degenerative and progredient diseases of the nervous system.
The possibility of vaccination of persons suffering from chronic diseases not listed in the list of contraindications is determined by the attending physician based on the patient's condition.
Carefully:Do not administer intravenously. In the offices where the vaccination is carried out, it is necessary to have medicines for anti-shock measures and relief of anaphylactic reaction.
The vaccinated should be monitored by a health worker within 30 minutes after immunization.
Pregnancy and lactation:Clinical studies have not been conducted.
Dosing and Administration:Vaccination is carried out twice with an interval of 4 weeks.
The vaccine is given intramuscularly, before you inject the ampoule with the drug, shake until a homogeneous suspension is obtained.
It is not suitable to use the drug in ampoules with broken integrity or marking, with expired shelf life,improper storage.
Opening of ampoules and the vaccination procedure are carried out with strict adherence to aseptic and antiseptic rules. The drug in the opened ampoule is not subject to storage.
The vaccination is recorded in the prescribed registration forms with the date of administration of the drug, dose, serial number and name of the manufacturer.
Side effects:Local and general reactions to the introduction of the vaccine are largely absent. Rarely at the injection site, there may be reactions in the form of soreness, redness and swelling of the skin. Individual reactions are possible in the form of increased fatigue, headache, dizziness, subfebrile temperature, rhinitis, pharyngitis, coughing, arthralgia, myalgia, nausea. These reactions usually disappear on their own in 1-3 days. In extremely rare cases with high individual sensitivity, allergic reactions can be observed.
Interaction:The vaccine can be administered against the background of basic therapy of the underlying disease. The vaccine can be used concomitantly with other inactivated vaccines.This should take into account contraindications to each of the vaccines used, the drugs must be injected into different parts of the body with different syringes.
Special instructions:All persons subject to inoculations should be examined by a doctor taking into account anamnestic data. On the day of vaccination, the vaccinated should be examined by a physician with mandatory thermometry. At a temperature above 37 ° C vaccinations are not carried out. The doctor is responsible for the correct administration of the vaccine.