Vaccination is conducted by the average medical staff under the guidance of a doctor. Primary immunization is carried out once per subcutaneously with syringe or needle-free methods.
Revaccination is carried out once. The first three revaccinations are performed annually. All subsequent revaccinations are carried out once every two years.
Before use, every ampoule with the vaccine is carefully examined. The vaccine can not be used if the integrity of the ampoule is damaged, the appearance of the preparation changes (foreign particles, unraveled lumps and flakes), the absence of a label, the expiration date. The ampoule with the vaccine is wiped 70% alcohol, saw the neck of the ampoule, cover with a sterile swab, break off the filed end of the ampoule.Using a sterile syringe with a needle in the ampoule, add 5.0 ml of the solvent - sterile sodium chloride solution 0.9% and shaken to form a homogeneous suspension of grayish-white color. The time of expansion of the vaccine should not exceed 5 minutes. Dissolved vaccine, preserved in aseptic conditions, can be used for 4 hours.
1. Vaccination with a syringe method. A 0.5 ml vaccine is injected subcutaneously into the area of the lower corner of the left scapula using a disposable syringe. The skin at the injection site is treated with 70% alcohol. Before each selection of the vaccine, the ampoule is shaken. The injection site is treated with 5% tincture of iodine.
2. Vaccination without a needle. The vaccine in a volume of 0.5 ml is injected subcutaneously into the outer surface of the upper third of the shoulder with a needleless injector with a protector, while strictly observing the instructions for its use. The place of administration of the vaccine before and after injection is treated as with a syringe method of vaccination.
The unused vaccine, used disposable syringes and needles must be inactivated by autoclaving at a temperature of (132 ± 2) ° C and a pressure of 2.0 kG / m2 within 90 minutes.
Parts of the needleless injector in contact with the vaccine are immersed in a 6% solution of hydrogen peroxide with the addition of 0.5% detergent such as "Progress" or "Astra" for 1 hour at a temperature of at least 50 ° C. The solution is used once. Then the pre-sterilization treatment of the injector is carried out:
a) rinsing under running water for 0.5 min;
b) soaking at full immersion in a washing solution at a temperature of 50 ° C for 15 minutes. Recipe 1 liter of detergent solution: 17 g perhydrol (27.5 g 33% hydrogen peroxide), 5 g detergent and 978 ml water;
c) washing in a washing solution with a ruff or a cotton-tampon swab of each object for 0.5 minutes;
d) rinsing under running water for 10 minutes;
e) rinsing with distilled water for 0.5 minutes each item;
e) Drying until the moisture disappears completely.
Sterilization of the parts of a needleless injector is carried out by autoclaving at a temperature of (132 ± 2) ° C and a pressure of 2.0 kG / m2 within 90 minutes.
Reaction to administration
Vaccinations with the vaccine can be accompanied by local reactions, the intensity of which depends on the individual characteristics of the vaccinated. After 24-48 hours after vaccination at the injection site, soreness, hyperemia,less often - infiltration with a diameter of up to 50 mm.