Validol with glucose (Validol with glucosae)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspsublingual tablets
Composition:

For one tablet:

Active substances:

Levomenthol solution in menthyl isovalerate (Validol) - 60 mg,

Dextrose monohydrate (glucose monohydrate) - 188 mg

Auxiliary substances: sugar (sucrose), aerosil (silicon dioxide colloid), stearic acid - a sufficient amount to obtain a tablet weighing 800 mg.

Description:

Tablets are flat-cylindrical, white or white with grayish patches of color, with a risk and facet, with a characteristic smell of menthol.

Pharmacotherapeutic group:Coronarodilating agent of reflex action
ATX: & nbsp
  • Other combination drugs for the treatment of heart disease
    • Pharmacodynamics:

    Has a sedative effect, has a moderate reflex vasodilator effect due to irritation of sensitive nerve endings. It stimulates the production and release of enkephalins, endorphins and a number of other peptides, kinins (due to stimulation of mucosal receptors), which take an active part in the regulation of vascular permeability, the formation of pain sensations. At sublingual admission, the therapeutic effect, on average, comes in 5 minutes, while up to 70% of the drug is released within 3 minutes.

    Dextrose monohydrate (glucose monohydrate) is involved in various metabolic processes in the body, is involved in metabolic processes.

    Pharmacokinetics:

    With sublingual use, it is absorbed from the mucous membrane of the oral cavity. After absorption, biotransformed in the liver and excreted by the kidneys in the form of glucuronides. Dextrose monohydrate is fully absorbed by the body, the kidneys are not excreted (appearance in the urine is a pathological sign).

    Indications:

    Functional cardialgia, neuroses, and also as an antiemetic for sea and air sickness.

    Contraindications:

    Hypersensitivity to the components of the drug.

    Children up to 3 years.

    Carefully:

    With caution, appoint patients with diabetes (the drug contains sugar).

    Dosing and Administration:

    Validol is prescribed to adults under the tongue. The tablet should be kept in the mouth under the tongue until it is completely resorbed. Take 1 tablet 2-3 times a day.

    The daily frequency and duration of reception is determined depending on the effectiveness of treatment. With insufficiently pronounced effect or, when in individual patients in the next 5 min.after taking the drug effect is not observed, you need to see a doctor to exclude a heart attack or prescribe another therapy. With strong and aggravating pain, especially against the background of previous heart diseases (angina pectoris, suffered myocardial infarction and others), you must call an ambulance.

    Side effects:

    With prolonged admission, mild nausea, lacrimation, dizziness may occur.

    These phenomena usually pass by themselves.

    Overdose:

    Symptoms: headache, nausea, agitation, a violation of the heart, a drop in blood pressure, depression of the central nervous system.

    Treatment: cancel the drug. Symptomatic therapy.

    Interaction:

    When combined with neurotropic drugs, the oppressive type of action enhances the inhibitory effect of the latter on the central nervous system.

    The simultaneous use of Validol with glucose and nitrates reduces the headache that occurs when they are used.

    Special instructions:

    1 tablet contains 188 mg of dextrose monohydrate (glucose monohydrate), 450 mg of sugar (sucrose), which corresponds to 0.054 XE, which should be taken into account by a patient with diabetes mellitus.

    Form release / dosage:

    Tablets are sublingual.

    Packaging:

    10 tablets in a planar cell package.

    1000 contour mesh packages with an equal number of instructions for use are placed in a cardboard box.

    Storage conditions:

    In a dry place, at a temperature of 12 to 18 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-010613/09
    Date of registration:25.12.2009 / 11.09.2012
    Expiration Date:Unlimited
    The owner of the registration certificate:AVEKSIMA, JSC AVEKSIMA, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp19.01.2017
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