Yonosterol (Ionosteril)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspsolution for infusions
Composition:

1000 ml of solution contain:

Active substances:

Sodium chloride

6.430 g

Potassium acetate

0.393 g

Sodium acetate

3.674 grams

Calcium acetate

0.261 g

Magnesium acetate (anhydrous)

0.261 g

Excipients:

Water for Injection

up to 1 liter

Electrolyte composition:

Na+

137.0 mmol / l,

TO+

4.0 mmol / l,

Ca++

1.65 mmol / l,

Mg++

1.25 mmol / l,

FROMl-

110.0 mmol / L,

CH3COO-

36.8 mmol / L

pH

5,0-7,0

Titrated acidity

1-10 mmol NaHE / L

Theoretical osmolality

291 mosm / l
Description:

A clear, colorless solution.

Pharmacotherapeutic group:Rehydrating agent
ATX: & nbsp
  • Solutions affecting the water-electrolyte balance
    • Pharmacodynamics:

    The action of the drug is aimed at correcting the water-electrolyte balance, acid-base state and water content. Imbalance of these factors is a severe pathophysiological syndrome, which causes disruption of metabolic processes and leads to serious, life-threatening consequences.

    Indications:

    Extracellular (isotonic) dehydration of various genesis: diarrhea, vomiting, fistula, drainage and intestinal obstruction.

    Primary volume replacement with blood loss and burns.

    Contraindications:

    Edema, hypertonic dehydration, severe renal failure.

    Pregnancy and lactation:

    Application is possible after assessing the risk-benefit ratio formother and fetus, do not exceed the recommended dosage.

    Dosing and Administration:

    For intravenous infusion.

    The maximum infusion rate is 3 ml / kg body weight per hour, i.e. 70 drops per minute, or 210 ml / hour with a body weight of 70 kg.

    The maximum dose is 40 ml / kg of body weight per day.

    The use of the drug Yonosteril can be continued for as long as required by the clinical condition of the patient.

    Side effects:

    When used in accordance with the instructions are not described.

    Overdose:

    Symptoms: overdose can lead to hyperhydration, electrolyte imbalance and the development of metabolic alkalosis.

    Treatment: immediate cessation of infusion, administration of diuretics, correction of electrolyte balance. If oligoanuria develops, hemodialysis may be required.

    Interaction:

    Simultaneous use with corticosteroids can lead to a delay in the body of sodium and water (edema and hypertension).

    Potassium-sparing diuretics (amiloride, spironolactone, triamterene, alone or in combination), suxamethonium, tacrolimus, cyclosporins, inhibitors angiogenesin-converting enzyme (ACE) - the risk of hyperkalemia.

    Cardiac glycosides - increase the toxicity of glycosides.

    Thiazide diuretics, Vitamin D - risk of hypercalcemia.

    Special instructions:

    It is necessary to constantly monitor the level of electrolytes of blood serum and water balance.

    To avoid the risk of developing air embolism when injected from a container or infusion system, before use it is necessary to completely remove air.

    Only for single dosing. Unused solution residues should be disposed of.

    Use immediately after opening the package.

    Apply with the observance of aseptic conditions.

    Use only a transparent solution that does not contain any mechanical inclusions from intact packaging.

    Effect on the ability to drive transp. cf. and fur:

    It was not reported on the effect of the drug on the ability to drive and work with machinery.

    Form release / dosage:Solution for infusion.
    Packaging:

    250 ml, 500 ml or 1000 ml in glass bottles for infusion solutions of hydrolytic class II glass, sealed with rubber (halobutyl) stoppers, coated with aluminum caps, equipped with plastic caps-control of the first opening (Hept. F.) 6 or 10 bottles together with holders for bottlesor without them, with instructions for use are placed in a cardboard box (for hospitals).

    To 250 ml, 500 ml or 1000 ml in a plastic bottle, equipped with a loop-holder for a dropper, sealed with a plastic combination of the proprietary cap "spike-shape". 10 or 20 bottles are placed together with instructions for use in a carton box (for hospitals).

    For 250 ml, 500 ml or 1000 ml in a polymer bag. For 10, 15, 20 or 30 bags, along with instructions for use, are placed in a carton box (for hospitals).

    Storage conditions:

    In the dark place at a temperature of no higher than 25 FROM.

    Keep out of the reach of children.

    Shelf life:

    5 years.

    Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:For hospitals
    Registration number:П N011824 / 01
    Date of registration:04.10.2011
    Expiration Date:Unlimited
    The owner of the registration certificate:Fresenius Kabi Deutschland GmbHFresenius Kabi Deutschland GmbH Germany
    Manufacturer: & nbsp
    Representation: & nbspFRESENIUS KABI DEYCHLAND GmbH FRESENIUS KABI DEYCHLAND GmbH Germany
    Information update date: & nbsp29.11.2017
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