Zedex (Zedex)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Similar drugsTo uncover
Dosage form: & nbspsyrup
Composition:

In 10 ml of syrup contains:

active substances: bromhexine hydrochloride 8.0 mg, dextromethorphan hydrobromide monohydrate 10.0 mg, ammonium chloride 100.0 mg;

Excipients: levomenthol 5.0 mg, sucrose 6000.0 mg, glucose (dextrose) 3500.0 mg, benzoic acid 7.00 mg, sodium benzoate 3.50 mg, sodium saccharinate 30.00 mg, propylene glycol - 363.30 mg, vanillin - 1.00 mg, dye sunset yellow - 0.67 mg, fruit flavor - 0.012 ml, purified water - up to 10.0 ml.

Description:Syrup - a thick, clear liquid of orange color with a smell of menthol.
Pharmacotherapeutic group:Antitussive combined (antitussive opioid + expectorant)
ATX: & nbsp
  • Antitussives in combination with mucolytics
    • Pharmacodynamics:

    Combined drug.

    Bromhexine has mucolytic (secretolitic), expectorant and weak antitussive effect. Mucolytic effect is associated with depolymerization and liquefaction of mucoprotein and mucopolysaccharide fibers.

    Dextromethorphan raises the threshold of sensitivity of the cough center of the medulla oblongata, without leading to the depression of the respiratory center, has an antitussive and sedative effect, does not cause an addictive effect to the drug and does not possess an analgesic effect.

    Ammonium chloride has expectorant properties.

    Indications:The drug is intended to alleviate the symptoms of "colds", flu, SARS, accompanied by cough.
    Contraindications:

    Hypersensitivity to the components of the drug; pregnancy and lactation; peptic ulcer (at the stage of exacerbation); simultaneous reception of other drugs containing substances that are part of Sedex; children's age till 6 years.

    Carefully:

    Hepatic and / or renal failure, bronchial asthma.

    Dosing and Administration:

    Adults and children over 12 years of age: inside 2 teaspoons 2-3 times a day.

    Children from 6 to 12 years: inside by 1 / 2-1 teaspoon 3-4 times a day.
    Side effects:Dyspeptic phenomena, exacerbation of peptic ulcer, allergic reactions (skin rash, rhinitis, etc.), increased serum transaminase levels, drowsiness, sleep disturbance, increased excitability (especially in children).
    Overdose:

    Dangerous for life overdose in the application of Bromhexine in humans are unknown. Possible symptoms are: nausea, vomiting and other gastrointestinal disorders.

    Dextromethorphan can cause excitation of the central nervous system.

    Treatment: gastric lavage, reception of activated charcoal, symptomatic therapy.
    Interaction:
    Zedex can be prescribed concomitantly with other drugs used in the treatment of bronchopulmonary diseases. Zedex is not prescribed concomitantly with antitussive agents (including those containing codeine). Bromhexine, part of Zedex, contributes to the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline, ampicillin, amoxicillin) into the lung tissue, but its combined use with salicylates, phenylbutazone and oxyphenbutazone can cause severe irritation of the gastric mucosa. Alcohol, which is part of the syrup, can change the effect of other medicines.

    Because the drug includes dextromethorphan, simultaneous use with MAO inhibitors is contra-indicated (it is possible to act on the CNS and expressed respiratory depression), amiodarone (can inhibit the metabolism of dextromethorphan in the liver and increase its toxicity), antidepressants - serotonin reuptake inhibitorsfluoxetine, paroxetine). Dextromethorphan can potentiate the analgesic effect of opioids.

    Special instructions:During treatment should refrain from drinking alcohol.
    Effect on the ability to drive transp. cf. and fur:

    Caution is observed when performing work that requires concentration of attention, increased speed of motor and mental reactions.

    Form release / dosage:Syrup.
    Packaging:

    100 ml in a bottle of transparent amber polyethylene, sealed with a screwed aluminum cover with the control of the first opening and a measuring plastic cup with a capacity of 10 ml.

    1 bottle with instructions for use in a cardboard box.

    Storage conditions:

    Store in a dry place, in tightly closed bottles, at a temperature not exceeding 30 ° C.

    Keep out of the reach of children.

    Shelf life:3 years. Do not use at expiration date
    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001270
    Date of registration:24.11.2011
    Expiration Date:24.11.2016
    The owner of the registration certificate:Vokhard LtdVokhard Ltd India
    Manufacturer: & nbsp
    Representation: & nbspVokhard Ltd., IndiaVokhard Ltd., India
    Information update date: & nbsp11.10.2017
    Illustrated instructions
      Instructions
      Up