Depending on the frequency of occurrence, the following groups of side effects are identified: very often (≥ 1/10), often (from ≥ 1/100 to <1/10), infrequently (from ≥ 1/1000 to <1/100), rarely from ≥ 1/10000 to <1/1000), very rarely (<1/10000), including individual messages.
From the nervous system:
Often: headache, dizziness.
Infrequent: sleep disorders, depression.
Rarely: drowsiness, agitation, tremor, paresthesia.
Very rarely: Aseptic meningitis.
From the digestive system:
Often: indigestion, abdominal pain, nausea, vomiting, diarrhea, heartburn.
Infrequent: gastritis, erosive-ulcerative lesions of the mucosa stomach and intestines (including perforation and bleeding), constipation, flatulence, increased levels of "liver" transaminases.
Rarely: dry mouth, esophagitis, melena, impaired liver function, stomatitis.
From the skin:
Infrequent: skin rash, itching, hives, alopecia.
Rarely: edematic syndrome, Stevens-Johnson syndrome, Lyell's syndrome, angioedema.
Very rarely: ecchymosis.
From the urinary system:
Rarely: dysuria, decreased glomerular filtration, interstitial nephritis, glomerulonephritis, papillary necrosis, nephrotic syndrome, peripheral edema, acute renal failure.
From the sense organs:
Infrequent: noise in the ears.
Rarely: impaired vision.
From the cardiovascular system:
Infrequent: development or exacerbation of heart failure, tachycardia.
Rarely: increased blood pressure.
From the hematopoiesis:
Rarely: agranulocytosis, leukopenia, anemia, thrombocytopenia, increased bleeding time.
On the part of the respiratory system:
Infrequently: rhinitis.
Rarely: pharyngitis, dyspnea, cough, bronchospasm.
Other:
Infrequent: anorexia, increased sweating, weight change, arthralgia.
Rarely: myalgia.
If any of the side effects listed in the manual are aggravated or you notice any other side effects not listed in the instructions, inform the doctor about it.