Clinical cases

The use of a dabigatran antagonist before thrombolysis

January 9, 2017
The material presents a clinical case illustrating the use of idaruzizumab (dabigatran antagonist) in a patient with ischemic stroke, which allowed avoiding hemorrhagic complications after intravenous thrombolysis.

Fracture of the penis

December 16, 2016
The material describes the clinical case of a penile fracture and the role of ultrasound in the diagnosis of this disease.

Apixaban in the treatment of left ventricular thrombosis

November 26, 2016
Left ventricular thrombosis is often detected in patients with impaired left ventricular function, for example, in dilated cardiomyopathy or postinfarction cardiac aneurysm. International recommendations suggest in such cases to prescribe anticoagulants to minimize the risk of embolism. For many years, only warfarin was used for this purpose. However, today anticoagulants of direct action relentlessly crowd the positions of warfarin. In this

Omalizumab. Application for urticarial vasculitis

October 26, 2016
The material describes the case of successful use of omalizumab with urticaria vasculitis.

Spherical acne in patients with purulent hydradenitis - the use of adalimumab

October 10, 2016
Acne conglobata is a type of acne that is characterized by a tendency to abscess and the formation of large comedones, which in turn entails the formation of hypertrophic and atrophic scars. This disease is associated with gross aesthetic defects, and this inevitably affects the quality of life of patients.Spherical acne is usually localized on the back, chest, shoulders, hips and face. Often

Myocardial infarction with thrombotic thrombocytopenic purpura

September 27, 2016
Thrombotic thrombocytopenic purpura is a disease characterized by the rapid development of microthrombosis in small-diameter blood vessels, thrombocytopenia of consumption and hemolytic anemia. The pathogenesis of the disease is associated with ADAMTS 13 protease dysfunction, which normally cleaves the von Willebrand factor (vWF) multimers. Thrombotic thrombocytopenic purpura manifests itself in a variety of neurological and

Hereditary telangiectasia with massive nasal bleeding

September 19, 2016
We present the clinical case of severe nasal bleeding against the background of Rundu-Weber-Osler disease.

Donepezil with cognitive disorders after traumatic brain injury

June 03, 2016
We represent the clinical case of a patient after a craniocerebral trauma, in which amnesia and attention deficit were significantly relieved after treatment with donepezil, risperidone and venlafaxine.

Sildenafil with temporary erectile dysfunction during the use of assisted reproductive technologies.

June 03, 2016
Four men who had temporary erectile dysfunction during assisted reproductive procedures, associated with in vitro fertilization (IVF), were able to sperm through sildenafil.

The use of eplerenone in primary hyperaldosteronism during pregnancy

May 23, 2016
Primary hyperaldosteronism (PA) in pregnancy is a rare case. In connection with the risks associated with pharmacotherapy and surgical intervention in pregnancy, it is often difficult to make a clinical decision in such situations. Here is described the case of short-term use of eplerenone for the treatment of arterial hypertension and hypokalemia in association with UA during pregnancy.

Spontaneous pregnancy after treatment with ulcers in a woman with symptomatic myoma of the uterus

April 19, 2016
A woman of African descent for 35 years was sent to treat uterine fibroids and impaired fertility. In the history of miscarriage of five pregnancies in a row during the previous 13 years at the gestational age from four to 16 weeks.The last pregnancy was interrupted at the gestational age of five weeks and required dilation and curettage. Embryopathological examination was not carried out. 12 months later, the patient was found
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