Treatment and prevention of gonorrhea

November 27, 2017

Drugs used to treat and prevent gonorrhea

Indications for use

LAN of choice

Alternative drugs

Gonorrhea in pregnant and lactating mothers

Ceftriaxone * intramuscularly 250 mg once

or

Erythromycin inside the first 2 days of 400 thousand units 6 times a day, then 400 thousand units 5 times a day (exchange dose of 8.8 million units)

or

Spectinomycin intramuscularly 2.0 g once

or

Azithromycin inside 1.0 g single-shot

Cefixim* inside 400 mg once

Conjunctivitis

Ceftriaxone * intramuscularly 1.0 g once

Ophthalmia of newborns

Ceftriaxone * intramuscularly 25-50 mg / kg body weight (not more than 125 mg) once or intravenously once a day for 2-3 days

or

Cefotaxime * intramuscularly 100 mg / kg body weight once plus copious body washings with isotonic sodium chloride solution

Prevention of ophthalmia in newborns

Silver nitrate external 1% aqueous solution once 2-3 drops in each eye

or

Erythromycin externally ophthalmic ointment 0.5% once

or

Tetracycline externally ophthalmic ointment 1% once

Pharyngitis

Ceftriaxone * intramuscularly 250 mg once

Anorectal infection

Ceftriaxone * intramuscularly 250 mg once

Cefuroxime intramuscularly 1.5 g once

or

Cefodizim intramuscularly 500 mg once

or

Azithromycin inside 1.0 g once

Complications of neonatal gonococcal infection (meningitis)

Ceftriaxone * intramuscularly or intravenously at a rate of 25-50 mg / kg body weight 1 time per day for 7 days (with meningitis - not less than 10-14 days)

or

Cefotaxime * intramuscularly or intravenously at a rate of 25 mg / kg body weight 2 times a day for 7 days (with meningitis - not less than 10-14 days)

Prevention of gonorrhea in newborns born to mothers with this infection

Ceftriaxone * intramuscularly at the rate of 25-50 mg / kg body weight (not more than 125 mg) once

or

Spectinomycin intramuscularly 40 mg / kg body weight (not more than 2.0 g) once

Note:* Cefixime, cefotaxime and ceftriaxone are not prescribed to patients with an allergy to cephalosporins or penicillin group drugs in the anamnesis.