Treatment and prevention of gonorrhea
Drugs used to treat and prevent gonorrhea
Indications for use | LAN of choice | Alternative drugs |
Gonorrhea in pregnant and lactating mothers | Ceftriaxone * intramuscularly 250 mg once or | Erythromycin inside the first 2 days of 400 thousand units 6 times a day, then 400 thousand units 5 times a day (exchange dose of 8.8 million units) or |
Spectinomycin intramuscularly 2.0 g once or | Azithromycin inside 1.0 g single-shot |
Cefixim* inside 400 mg once | |
Conjunctivitis | Ceftriaxone * intramuscularly 1.0 g once | |
Ophthalmia of newborns | Ceftriaxone * intramuscularly 25-50 mg / kg body weight (not more than 125 mg) once or intravenously once a day for 2-3 days or | |
Cefotaxime * intramuscularly 100 mg / kg body weight once plus copious body washings with isotonic sodium chloride solution | |
Prevention of ophthalmia in newborns | Silver nitrate external 1% aqueous solution once 2-3 drops in each eye or | |
Erythromycin externally ophthalmic ointment 0.5% once or | |
Tetracycline externally ophthalmic ointment 1% once | |
Pharyngitis | Ceftriaxone * intramuscularly 250 mg once | |
Anorectal infection | Ceftriaxone * intramuscularly 250 mg once | Cefuroxime intramuscularly 1.5 g once or |
| Cefodizim intramuscularly 500 mg once or |
| Azithromycin inside 1.0 g once |
Complications of neonatal gonococcal infection (meningitis) | Ceftriaxone * intramuscularly or intravenously at a rate of 25-50 mg / kg body weight 1 time per day for 7 days (with meningitis - not less than 10-14 days) or | |
Cefotaxime * intramuscularly or intravenously at a rate of 25 mg / kg body weight 2 times a day for 7 days (with meningitis - not less than 10-14 days) | |
Prevention of gonorrhea in newborns born to mothers with this infection | Ceftriaxone * intramuscularly at the rate of 25-50 mg / kg body weight (not more than 125 mg) once or | |
Spectinomycin intramuscularly 40 mg / kg body weight (not more than 2.0 g) once | |
Note:* Cefixime, cefotaxime and ceftriaxone are not prescribed to patients with an allergy to cephalosporins or penicillin group drugs in the anamnesis.