Active substanceInterferon alfa-2bInterferon alfa-2b
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  • Dosage form: & nbsp
    lyophilizate for the preparation of a solution for intranasal administration

    Composition:

    Active substances: Interferon alfa-2b human recombinant - no less than 50 000 ME.

    Excipients: polyglucin, sodium chloride, sodium phosphate monosubstituted 2-water, sodium phosphate disubstituted.

    Description:The preparation is a lyophilized powder or a porous mass of white or light yellow color, hygroscopic; after dissolving in 5 ml of water for injection, a clear, colorless or pale yellow solution is formed, without sediment and foreign inclusions.
    Pharmacotherapeutic group:Immunomodulators. Antiviral drugs
    ATX: & nbsp

    L.03.A.B.05   Interferon alfa-2b

    Pharmacodynamics:

    ALFARONE is a human recombinant interferon-alpha-2b-protein synthesized by the Escherichia coli strain. in the genetic apparatus of which the human leukocyte interferon alpha-2b gene is embedded. Alfarone is identical to human leukocyte interferon alpha-2b.

    Has antiviral, immunomodulatory, anti-inflammatory, antimicrobial effect.

    Indications:Prevention and treatment of acute respiratory viral infection, influenza in adults and children in the initial stages of the disease.
    Contraindications:Individual intolerance to interferon preparations, allergic diseases, taking place in severe form.
    Dosing and Administration:

    Intranasal. The contents of the vial are dissolved in 5 ml of water for injection. At the first signs of the flu, ARVI: adults - 3 drops in each nasal passage 5-6 times a day (single dose - 3000 ME, daily - 15000-18000 ME), newborns and children under 1 year - 1 drop 5 times per day (single dose 1000 ME, daily dose - 5000 ME), children from 1 to 3 years - 2 drops 3-4 times a day (single dose - 2000 ME, daily - 6000-8000 ME), from 3 to 14 years - 2 drops 4-5 times a day (single dose - 2000 ME, daily - 8000-10000 ME) for 5 days. For the prevention of acute respiratory viral infection and influenza:

    In case of contact with the patient and / or during supercooling - according to the age-related dosage 2 times a day for 5-7 days. If necessary, preventive courses are repeated. When a single contact is enough, one instillation. With a seasonal increase in the incidence - according to the age dosage in the morning after 1-2 days.

    After instillation it is recommended to massage the wings of the nose with your fingers for several minutes to distribute the drug evenly in the nasal cavity.

    Side effects:Not noted.
    Interaction:Simultaneous use of intranasal vasoconstrictors is not recommended (promotes additional drying of the nasal mucosa).
    Form release / dosage:
    Liofilizate for the preparation of solution for intranasal administration 50 000 ME.
    Packaging:In the vial, complete with water for injection 5 ml.
    Storage conditions:In a dry, the dark place at a temperature of not more than +10 ° C. The drug solution should not be stored for more than 10 days in the refrigerator (do not freeze).
    Shelf life:2 years. Do not use after the expiration date.
    Terms of leave from pharmacies:On prescription
    Registration number:LS-001041
    Date of registration:27.08.2010 / 26.05.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:NPP FARMAKLON, LLC NPP FARMAKLON, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp18.07.2017
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