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Dosage form: & nbspcoated tablets
Composition:

For one tablet:

active matter: bile of large cattle dry - 80 mg, garlic dried - 40 mg, activated carbon - 25 mg, nettle leaves - 5 mg;

auxiliary substances (core): magnesium oxide (magnesium, oxide) - 11 mg, potato starch - 43 mg, talc - 3 mg, silicon dioxide colloid (aerosil) - 1 mg, calcium stearate - 2 mg;

auxiliary substances (shell): sucrose (sugar) - 164 mg, magnesium hydroxycarbonate (magnesium carbonate basic) - 35 mg, silicon dioxide colloid (aerosil) - 2 mg, titanium dioxide - 3 mg, povidone (polyvinylpyrrolidone) - 2 mg, talc - 3 mg, tropeolin O 0.04 mg, beeswax - 0.2 mg.

Description:

Tablets are round, biconvex, covered with a coating of light yellow color. Three layers are visible on the cross-section: the core is gray-black with inclusions; the middle layer is white and the outer layer is light yellow.

Pharmacotherapeutic group:Cholagogue
ATX: & nbsp
  • Other drugs for the treatment of bile duct diseases
  • Pharmacodynamics:

    Choleretic (cholekinetic and choleretic) remedy, reduces the processes of putrefaction and fermentation in the intestine. Strengthens the secretory function of liver cells, reflexively increases the secretory and motor activity of the gastrointestinal tract (GIT). Strengthens the formation of bile and bile acids.

    Act bile is due to the reflex influence on the secretory function of the liver parenchyma. Bile also enhances the secretory and motor function of the digestive tract.

    Substances contained in garlic, strengthen the secretory and motor function of the gastrointestinal tract, stimulate the secretion of bile.

    Leaves of nettle possess cholagogue and anti-inflammatory properties.

    Activated carbon is an adsorbent that binds toxic substances in the digestive tract.
    Pharmacokinetics:

    Allochol is well absorbed into the digestive tract. Cholic and chenodeoxycholic acid, contained in Allochol, are metabolized in the liver: conjugated to amino acids, secreted in bile, whence they are again released into the intestine, then partially reabsorbed; the remainder is excreted through the intestine.

    Indications:

    As part of complex therapy for chronic reactive hepatitis, cholangitis, beskamennom (noncalcular) cholecystitis, biliary dyskinesia of the hypokinetic type, atonic constipation, postcholecystectomy syndrome.

    Contraindications:

    Hypersensitivity, calculous cholecystitis, obstructive jaundice, acute hepatitis, acute and subacute liver dystrophy,stomach ulcer and duodenal ulcer (in the acute phase), acute pancreatitis, children under 12 years of age, sugar / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption (as in sucrose).

    Carefully:Diabetes mellitus (in the composition of the drug contains sucrose).
    Pregnancy and lactation:

    Application of the drug in periods pregnancy and lactation is possible on the recommendation of the doctor, when the benefit to the mother is greater than the risk for the fetus or the baby.

    Dosing and Administration:

    Inside, after eating, 1-2 tablets 3-4 times a day for 3-4 weeks.

    Children over 12 years of age: 1 tablet 3 times a day (after eating) for 3-4 weeks.

    Repeated courses are conducted at intervals of 3 months.

    Side effects:

    Diarrhea, allergic reactions, increased activity of "liver" transaminases in blood serum.

    Overdose:

    Diarrhea, nausea, heartburn, itchy skin are possible.

    Treatment: symptomatic.

    Interaction:

    Preparations containing aluminum hydroxide, colestramine, colestipol reduce absorption and reduce the effect of the drug. Simultaneous reception is inexpedient.

    Special instructions:Not described.
    Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive and perform other potentially hazardous activities that require special attention and quick reactions.
    Form release / dosage:

    The tablets covered with a cover.

    Packaging:

    For drugs produced at OAO Irbitsky Chemical Plant,:

    50 tablets per can of polymeric materials.

    For 10, 20, 24, 50 tablets in a contour mesh box made of polyvinylchloride film and foil aluminum printed varnished.

    By 2, 3, 4 or 5 contour cell packs of 10 tablets or 1 can of polymeric materials with instructions for medical use are placed in a pack of cardboard.

    Contoured cell packs of 10, 20, 24 or 50 tablets with an equal number of instructions for medical use or a pack of cardboard are placed in a group package.

    For drugs produced at LLC "Avexima Siberia":

    50 tablets per can of polymeric materials.

    10 tablets per contour cell packaging made of polyvinylchloride film and aluminum foil foil lacquered.

    For 1, 2, 3, 4 or 5 contour cell packs of 10 tablets or 1 can of polymeric materials with instructions for medical use are placed in a pack of cardboard.

    Storage conditions:

    Store in a dry place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    4 years.

    After expiration date the drug should not be used.

    Terms of leave from pharmacies:Without recipe
    Registration number:P N002403 / 01
    Date of registration:25.05.2009 / 07.04.2017
    Expiration Date:Unlimited
    The owner of the registration certificate:AVEKSIMA, JSC AVEKSIMA, JSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp10.07.2017
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