Active substanceTetrahydroxyglucopyranosylxantheneTetrahydroxyglucopyranosylxanthene
Similar drugsTo uncover
  • Alpisarin®
    pills inwards 
  • Alpisarin® ointment
    ointment locally externally 
  • Dosage form: & nbspointment for external and local use
    Composition:

    Active substance:

    Tetrahydroxyglucopyranosylxanthene 2.0 g or 5.0 g;

    (Alpisarin®) (in terms of 100% substance)

    Excipient:

    Vaseline medical - to obtain 100.0 g of ointment

    Description:Homogeneous mass of light yellow color with a greenish tinge or without a shade.
    Pharmacotherapeutic group:An antiviral agent of plant origin
    ATX: & nbsp

    J.05.A.X   Other antiviral drugs

    Pharmacodynamics:

    Alpizarin® is obtained from technical mangiferin, isolated from mango leaves of Indian - Mangifera indica L. family sumacovye - Anacardiaceae.

    Pharmacokinetics. With external and / or topical application, Alpizarin® does not have a significant systemic effect.

    Pharmacokinetics:

    The inhibitory effect of the drug on the reproduction of the virus is especially evident in the early stages of its development.

    Alpisarin® has immunostimulating properties with respect to cellular and humoral immunity, the ability to induce gamma-interferon production in blood cells.

    Alpisarin® inhibits the growth of Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus, Mycobacterium tuberculosis) bacteria,. fungi (Microsporum canis) and the simplest parasites (Entamoeba histolytica, Trichomonas vaginalis). The mechanism of action of the drug is based on the ability to suppress the activity of bacterial nuclease.

    Alpisarin® has an anti-inflammatory (anti-edema) effect.

    Indications:

    Adults and children over 1 year of age in complex therapy of acute and recurrent forms of diseases caused by the herpes virus (Herpes simplex and Herpes zoster) different localization (including genital), viral diseases of the oral mucosa (aphthous stomatitis, lichen planus), shingles, herpeticiform eczema of Kaposi, cytomegalovirus infection, chicken pox.

    Contraindications:

    Hypersensitivity to the components of the drug. Pregnancy. Children up to 1 year.

    Carefully:lactation period (breastfeeding).
    Dosing and Administration:

    Outer, local.

    Ointment is applied externally / locally 4-6 times a day: for skin lesions, adults are prescribed 5 % ointment, children - 2%; on the mucous membranes of adults and children - 2% ointment. The ointment is applied in a thin layer and lightly rubbed.

    The therapeutic effect of the drug is most pronounced when it is prescribed in the initial period of the disease or relapse.The duration of treatment depends on the form and severity diseases:

    - In acute and recurrent forms of herpes simplex extragenital localization with a single rash, the ointment is applied to the lesion for 3-5 days. In case of common rashes, as well as in the presence of fever, lymphadenopathy and other common phenomena, the ointment is applied for 5-14 days.

    - With herpes form Kaposi eczema and cytomegalovirus infection, ointment is used at the same age dosages for 7-21 days in complex therapy.

    - In genital herpes 2% ointment is applied to the affected areas 4 to 6 times a day for 7-10 days.

    - In case of viral diseases of the oral mucosa (aphthous stomatitis), ointment is applied to the affected areas within 5-15 days, with erosive-ulcerative form of the red flat lichen of the oral mucosa within 2-4 weeks.

    - In diseases caused by Herpes zoster (shingles) and Varicella zoster (chickenpox) topically apply ointment 2 % (children) or 5% (adults) on the lesion for 5-21 days.

    When relapses, repeated courses of treatment with the drug are carried out.

    Side effects:Allergic reactions are possible.
    Overdose:To date, cases of drug overdose have not been reported.
    Interaction:

    With external use of the drug, interaction with other drugs has not been identified. The drug can be used in complex treatment, including with drugs of systemic (generalized) action.

    Special instructions:

    The inhibitory effect of the drug on the reproduction of the virus is especially evident in the early stages of its development.

    In the case of common rashes, as well as in the presence of fever, lymphadenopathy and other common phenomena in combination with ointment for topical and external use, use Alpisarin® in tablets.

    Effect on the ability to drive transp. cf. and fur:

    The use of the drug does not affect the performance of potentially dangerous activities requiring concentration of attention and speed of psychomotor reactions (transport management, work with moving mechanisms, dispatcher and / or operator work).

    Form release / dosage:

    Ointment for external and local use 2 % and 5%.

    For 5 g, 10 g and 20 g in aluminum tubes with an internal lacquer coating and bush of high-density polyethylene.Each tube, together with instructions for medical use, is placed in a pack of cardboard for consumer packaging.

    Packaging:Tubes aluminum with internal lacquer coating and bushon made of high-density polyethylene / Aluminum tube, medical instruction, cardboard package / - Cardboard package for consumer packaging
    Storage conditions:

    Store in a dark place at a temperature of 12 to 15 'C.

    Keep out of the reach of children.

    Shelf life:5 years. Do not use after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:PL-000856
    Date of registration:14.10.2011
    The owner of the registration certificate:FARMTSENTR VILAR, ZAO FARMTSENTR VILAR, ZAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp26.09.2015
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