Amintaks (Amintax)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspVaginal suppositories
Composition:

Composition per suppository:

Active substances: neomycin 35000 ME, nystatin - 100,000 ME, polymyxin B-35,000 ME.

Excipients: macrogol 400 and macrogol 1500 in the ratio (5:95) to obtain a suppository with a mass of 2400 mg.

Description:Suppositories yellow, torpedo-shaped. An air rod and / or a funnel-shaped depression are allowed.
Pharmacotherapeutic group:Antibiotic combined (antibiotics: aminoglycoside + polyene + cyclic polypeptide)
ATX: & nbsp
  • Nystatin in combination with other drugs
    • Pharmacodynamics:

    Combined drug, the effect of which is due to its constituent components. It has antibacterial, bactericidal and antifungal action. Neomycin and polymyxin They are active against many gram-negative and gram-positive microorganisms; Streptococcus spp. and anaerobic bacteria are insensitive to these antibiotics. Nystatin has a fungicidal effect against fungi of the genus Candida.

    Improves trophic processes in the vaginal mucosa.

    Pharmacokinetics:

    Evenly distributed over the vaginal mucosa, exerting local bactericidal and fungicidal action. Virtually not absorbed from the surface of the vaginal mucosa.

    Indications:

    Treatment.

    Infectious-inflammatory diseases caused by sensitive microorganisms: nonspecific, fungal, mixed vaginitis, vulvovaginitis and cervicovaginitis.

    Prevention.

    Preoperative prophylaxis of infectious complications in gynecological interventions;

    - before and after diathermocoagulation of the cervix;

    - before intrauterine diagnostic procedures;

    - before giving birth.

    Contraindications:

    Hypersensitivity to any component of the drug.

    I trimester of pregnancy.

    Lactation period.

    Pregnancy and lactation:

    Application during pregnancy in the II and III trimesters is possible only according to the doctor's prescription in those cases when the expected benefit for the mother exceeds the potential risk to the fetus.

    If you need to use the drug during lactation, breastfeeding is stopped.

    During the period of breastfeeding, the use of the drug is contraindicated.
    Dosing and Administration:

    For intravaginal application.

    Lying on the back, the suppository is injected deep into the vagina in the evening before going to bed.

    The course of treatment is 12 days.

    Preventive course 6 days.

    In case of missed use of the drug, the treatment should be resumed in the usual dose.

    If there is no improvement after treatment, or the symptoms worsen, or new symptoms appear, it is necessary to consult a doctor.

    Use the drug only according to the indications, the method of administration and the doses indicated in the instructions.

    Side effects:

    Allergic reactions, burning, itching, irritation in the vagina. Allergic contact eczema. With prolonged use, a systemic manifestation of side effects of aminoglycosides is possible.

    If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

    Overdose:

    In accordance with the instructions for use, an overdose is unlikely. If the drug is taken orally, systemic effects (nephrotoxicity, ototoxicity) may occur. With prolonged use, the risk of allergic contact eczema increases.

    Treatment: symptomatic therapy.

    Interaction:

    Not studied.

    Special instructions:

    Before using the drug, a preliminary smear extraction and bacteriological analysis are necessary.

    In case of kidney failure, consult a doctor. The timing of the drug should be limited in order to prevent the formation of resistance to it of certain pathogens and the risk of reinfection.

    During treatment it is not recommended to use caps and condoms from latex. There is a risk of rupture of the condom or diaphragm. It is not recommended to use in combination with spermicides, possibly reducing the activity of the drug.

    Do not interrupt treatment during menstruation.

    During treatment, it is necessary to refrain from using intravaginal tampons.

    In the case of local intolerance, the development of an allergic reaction, the occurrence of side effects should stop using the drug and consult a doctor.

    If clinical signs of infection persist after completion of treatment, a second microbiological study should be conducted to confirm the diagnosis.

    During treatment it is recommended to abstain from sexual intercourse.
    Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
    Form release / dosage:Suppositories are vaginal.
    Packaging:

    For 5 suppositories in a contiguous cell pack of PVC / PE film. Two contoured cell packs along with instructions for medical use in a pack of cardboard.

    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date printed on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:LP-004173
    Date of registration:03.03.2017
    Expiration Date:03.03.2022
    The owner of the registration certificate:PATENT-FARM, CJSC PATENT-FARM, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp30.03.2017
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