Staphylococcus anatoxin purified (Anatoxinum staphylococcus)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Active substanceStaphylococcus aurexinStaphylococcus aurexin
Dosage form: & nbsphypodermic solution
Composition:

Staphylococcal anaphylaxis is a staphylococcal toxin rendered with formalin and heat, purified from ballast proteins.

1.0 ml of the drug contains 10 to 14 EC (units of binding) of staphylococcal anatoxin.

The drug does not contain preservatives and antibiotics.

Description:

The clear liquid is colorless or light yellow in color.

Pharmacotherapeutic group:MIBP
ATX: & nbsp

J.07.A.X   Other vaccines for the prevention of bacterial infections

Pharmacodynamics:The drug causes the formation of specific antibodies against Staphylococcal exotoxin.
Indications:Specific immunotherapy of acute and chronic (in the stage of exacerbation) of staphylococcal infection in adults.
Contraindications:

Contraindications for the use of Staphylococcal anatoxin purified,are: acute infectious and non-infectious diseases of not staphylococcal etiology, chronic diseases of not staphylococcal etiology in the stage of exacerbation or decompensation - vaccinations are given no earlier than 1 month after recovery (remission).

Carefully:

Use with caution, if there is a history of severe allergic reactions (anaphylactic shock, Quincke's edema); during pregnancy (because there is insufficient data on the safety of the drug in pregnant women).

Dosing and Administration:

Staphylococcal anoxin, purified enter subcutaneously under the lower angle of the scapula, alternating the right and left sides with each subsequent injection. Intramuscular use of the drug is not allowed.

The preparation contained in ampoules with broken integrity, marking, with changing physical properties (presence of turbidity, flakes), with expired shelf life, with violation of storage conditions is not suitable for use. Opening of ampoules and administration of the drug to patients are carried out with strict adherence to aseptic and antiseptic rules.

The drug in the opened ampoule is not subject to storage.

The full course of treatment includes 7 injections of the drug, performed with an interval of 2 days, in the following incremental doses: 0.1-0.3-0.5-0.7-0.9-1.2-1.5 ml.

With a rapid clinical effect, the course of therapy at the discretion of the attending physician can be reduced to 5 injections.

Side effects:

The administration of the drug may be accompanied by general, local and focal reactions.

General reactions are characterized by mild weakness, malaise, occasionally with an increase in temperature to 37.5 ° C.

Local reactions are characterized by hyperemia and mild soreness at the injection site, disappearing after 1-2 days.

Often, after the injection of the drug, a focal reaction may occur. exacerbation of the process in the place of its localization.

The occurrence of these reactions is not a contraindication for continuing treatment. However, in the presence of simultaneous general and local reactions, the interval between the previous and subsequent injections of the drug is recommended to be increased by 1 day. The development of the focal reaction does not require an increase in the interval between injections.

Interaction:

Treatment with anthraxin staphylococcal purified can be carried out simultaneously with other general and local therapy, except for immunoglobulins and antistaphylococcal plasma.

Form release / dosage:Solution for subcutaneous administration.
Packaging:In ampoules of 1.0 ml. The pack contains 10 ampoules and instructions for use.
Storage conditions:

Transportation. In accordance with SP 3.3.2.1248-03 at a temperature of 2 to 8 ° C. Freezing is not allowed.

Storage conditions. AT accordance with JV 3.3.2. 1248-03 at a temperature of 2 to 8 ° C in a dry, dark place. Freezing is not allowed.
Shelf life:2 years.
Terms of leave from pharmacies:On prescription
Registration number:P N000648 / 01
Date of registration:27.02.2008 / 19.05.2015
Expiration Date:Unlimited
The owner of the registration certificate:MEDGAMAL (a branch of the Research Institute of Epidemiology and Microbiology named after NF Gamalei RAMS GU) MEDGAMAL (a branch of the Research Institute of Epidemiology and Microbiology named after NF Gamalei RAMS GU) Russia
Manufacturer: & nbsp
Information update date: & nbsp01.09.2017
Illustrated instructions
    Instructions
    Up