Combined drug, has antipyretic, anti-inflammatory, analgesic, angioprotective, anticongestive action. Pharmacological activity of the drug is due to the properties of the active substances that make up its composition.
Acetylsalicylic acid suppresses anti-inflammatory factors, exudative and proliferative phases of inflammation due to inhibition of cyclo-genase, inhibits synthesis or inactivates mediators of inflammation. It has analgesic, antipyretic and anti-inflammatory action, inhibits platelet aggregation.
Ascorbic acid takes part in many types of oxidation-reduction reactions in the body, inhibits the processes of peroxidation of lipids, proteins and other components of the cell, thus protecting it from damage. Ascorbic acid increases the concentration of interferon in the blood, this is associated with its membrane-stabilizing effect and immunomodulating effect. Ascorbic acid is able to accumulate in leukocytes, increasing their phagocytic activity, which increases antimicrobial and antiviral protection. Activates the biosynthesis of corticoid hormones in the adrenal cortex and thereby stimulates the adaptive processes of the body under stress.
Rutozid angioprotective agent. Belongs to a group of bioflavonoids that can be used to build biologically important compounds in a cell, in particular ubiquinone. It is able to reduce capillary bleeding by strengthening the walls of blood vessels, the permeability of which increases during a viral infection. Rutozid has a beneficial effect on maintaining a normal level of the immune system.
Metamizol sodium - an analgesic non-narcotic agent, a derivative of pyrazolone, non-selectively blocks COX (cyclooxygenase) and reduces the formation of prostaglandins from arachidonic acid. It prevents painful impulses, raises the threshold of excitability of thalamic centers of pain sensitivity, increases heat transfer. Has analgesic, antipyretic and some spasmolytic (with respect to the smooth muscles of the urinary and biliaryways) action.
Diphenhydramine - competitive blocker H1-gistaminovyh receptors. It has a pronounced antihistaminic activity (weakens the body's response to endogenous and exogenous histamine). In addition, it has a local anesthetic effect, relaxes smooth muscles as a result of direct spasmolytic action, blocks to a moderate extent the cholinergic receptors of vegetative nervous nodules. Reduces the permeability of capillaries, prevents histamine edema of tissues and histamine hypotension and thereby reduces vascular permeability, eliminates edema and hyperemia of the nasal mucosa, perspiration in the throat, allergic reactions from the upper respiratory tract. An important feature of diphenhydramine is its sedative effect.
Calcium gluconate -Sa2+-containing drug. Calcium ions are necessary for the implementation of the process of transmission of nerve impulses, reduction of skeletal and smooth muscles, the activity of the heart muscle, the formation of bone tissue, clotting of blood. Calcium ions reduce the permeability of cells and the vascular wall, prevent the development of inflammatory reactions, increase the resistance of the body to infections.