Clinical and pharmacological group: & nbsp

Vitamins and vitamin-like remedies

Included in the formulation
  • Asvitol®
    pills inwards 
  • Ascovit®
    pills inwards 
    VALEANT, LLC     Russia
  • Ascovit®
    powder inwards 
    VALEANT, LLC     Russia
  • Ascovit®
    pills inwards 
    Natur Product Europe BV     Netherlands
  • Ascorbic acid
    pills inwards 
    ALTAYVITAMINS, CJSC     Russia
  • Ascorbic acid
    solution w / m in / in 
  • Ascorbic acid
    solution w / m in / in 
  • Ascorbic acid
    pills inwards 
    VEROPHARM SA     Russia
  • Ascorbic acid
    solution w / m in / in 
    ATOLL, LLC     Russia
  • Ascorbic acid
    powder inwards 
  • Ascorbic acid
    powder inwards 
    MARBIOFARM, OJSC     Russia
  • Ascorbic acid
    powder inwards 
    MEDISORB, CJSC     Russia
  • Ascorbic acid
    powder inwards 
    OZONE, LLC     Russia
  • Ascorbic acid
    pills inwards 
    BIOSINTEZ, PAO     Russia
  • Ascorbic acid
    solution w / m in / in 
    BIOSINTEZ, PAO     Russia
  • Ascorbic acid
    solution w / m in / in 
  • Ascorbic acid
    solution w / m in / in 
  • Ascorbic acid
    powder inwards 
    LYUMI, LLC     Russia
  • Ascorbic acid
    pills inwards 
  • Ascorbic acid
    pills inwards 
    MARBIOFARM, OJSC     Russia
  • Ascorbic acid
    solution w / m in / in 
    DALHIMFARM, OJSC     Russia
  • Ascorbic acid
    solution w / m in / in 
  • Ascorbic acid
    solution w / m in / in 
    ESKOM NPK, OAO     Russia
  • Ascorbic acid
    solution w / m in / in 
  • Ascorbic acid
    pills inwards 
    MEDISORB, CJSC     Russia
  • Ascorbic acid
    solution w / m in / in 
    BIOCHEMIST, OJSC     Russia
  • Ascorbic acid
    pills inwards 
    VALENTA PHARM, PAO     Russia
  • Ascorbic acid
    solution w / m in / in 
  • Ascorbic acid
    powder inwards 
    ROSFARM, CJSC     Russia
  • Ascorbic acid
    pills inwards 
    DALHIMFARM, OJSC     Russia
  • Ascorbic acid
    powder inwards 
    MELIGEN FP, CJSC     Russia
  • Ascorbic acid
    powder inwards 
  • Ascorbic acid bufus
    solution w / m in / in 
    UPDATE OF PFC, CJSC     Russia
  • Ascorbic acid-Vial
    solution w / m in / in 
    VIAL, LLC     Russia
  • Ascorbic acid-SOLOfarm
    solution w / m in / in 
    GROTEKS, LLC     Russia
  • Ascorbic acid-UBF
    pills inwards 
    URALBIOFARM, OJSC     Russia
  • ALTAYVITAMINS, CJSC     Russia
  • Vaginorm-C®
    pills the vagina. 
    Polikhem S.A.     Luxembourg
  • Vitamin C
    pills inwards 
    Soko Stark DOO.     Serbia
  • Rostvert
    pills inwards 
  • Setwork 500
    capsules inwards 
  • Cevicap®
    drops inwards 
  • Celascon® Vitamin C
    pills inwards 
    Zentiva as.     Czech Republic
  • Celascon® effect Vitamin C
    capsules inwards 
    Zentiva c.s.     Czech Republic
  • Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):

    VED

    ONLS

    Minimal chemist's assortment

    АТХ:

    A.11.G.A.01   Ascorbic acid

    Pharmacodynamics:

    Antioxidant. Participates in the synthesis of intracellular collagen. Suppresses the activity of hyaluronidase, participates in the exchange of iron and glucose.

    Reduces the body's need for vitamins A, E, B1 and B2, pantothenic and folic acid.

    The human body is not synthesized.

    Regulates the transport of hydrogen ions in oxidation-reduction reactions, including in the process at any stage of the Krebs cycle. Participates in the regulation of carbohydrate metabolism. Provides absorption of iron in the intestine, transferring it from trivalent into a divalent form, facilitating its incorporation into heme. Participates in the formation of tetrahydrofolic acid, the synthesis of steroid hormones, norepinephrine and adrenaline, collagen, prothrombin, glycogen. Inactivates hyaluronidase, activating the regeneration of tissues and normalizing the permeability of capillaries. Disinfects toxins and has an antioxidant effect, catching free radicals. He takes an active part in the regulation of immune processes: enhances the formation of antibodies, phagocytic activity and the synthesis of interferon. It inhibits the release of histamine and strengthens its degeneration, suppresses the release of mediators of inflammation and allergic reactions.

    Pharmacokinetics:

    Completely absorbed from the gastrointestinal tract after ingestion. It binds to plasma proteins in 25%. Normally, the concentration of ascorbic acid in the blood: 15-20 mcg / ml.The concentration of ascorbic acid in erythrocytes and plasma is lower than in platelets and leukocytes.

    Ascorbic acid is oxidized to dehydroascorbic acid, metabolized to inactive ascorbate-2-sulfate and oxalic acid, then excreted in the urine. In cases of exceeding the dose (more than 200 mg) ascorbic acid is eliminated by the kidneys in an unchanged form.

    Indications:

    It is used for hypo- and avitaminosis C, increased need for ascorbic acid during pregnancy and lactation, in the period of intensive growth and reconvalescence. Promotes rapid recovery with increased physical exertion.

    IV.E50-E64.E54   Insufficiency of ascorbic acid

    XXI.Z70-Z76.Z73.0   Overwork

    XXI.Z40-Z54.Z54   Condition of recovery

    XXI.Z70-Z76.Z73.3   Stress condition, not elsewhere classified

    Contraindications:

    Individual intolerance.

    Carefully:

    Deficiency of glucose-6-phosphate dehydrogenase, diabetes mellitus, hyperoxaluria, thalassemia, nephrolithiasis.

    Pregnancy and lactation:Recommendations for FDA - Category B. In pregnancy and lactation, the dose of the vitamin is doubled.
    Dosing and Administration:

    Is taken orally, dosages in terms of ascorbic acid.

    Prophylactic dose for adults: 50-100 mg per day, children - 25 mg per day.

    Therapeutic dose for adults: 50-100 mg 3-5 times a day, children - 50-100 mg 2-3 times a day.

    During pregnancy and lactation: 300 mg per day 15 days, then 100 mg per day.

    The highest daily dose: 500 mg.

    The highest single dose: 300 mg.

    Side effects:

    Irritation of the mucous membrane of the gastrointestinal tract: intestinal spasm, nausea, vomiting.

    Hyperoxaluria, nephrocalcinosis.

    Hyperglycemia, glucosuria.

    Allergic reactions.

    Overdose:

    With the intake of more than 1 g there is a headache, the excitability of the central nervous system increases.

    Interaction:

    Fresh vegetable and fruit juices, alkaline drink - reduce the absorption of ascorbic acid in the gastrointestinal tract.

    Simultaneous use of the drug with acetylsalicylic acid - the effectiveness of vitamin C is reduced by one third due to a decrease in absorption in the gastrointestinal tract.

    The intake of ascorbic acid with iron preparations increases their effectiveness.

    Reduces the effectiveness of heparin and indirect anticoagulants.

    Reduces the effectiveness of neuroleptics - phenothiazine derivatives.

    Reduces the chronotropic effect of isoprenaline.

    Barbiturates accelerate the release of ascorbic acid in the urine.

    Tetracycline also increases the elimination of ascorbic acid.

    Special instructions:

    Monitoring of kidney function and blood pressure, due to the increased synthesis of corticosteroid hormones.

    With prolonged consumption of the drug, it is possible to suppress the functions of the Langerhans islets of the pancreas - it is necessary to monitor the blood glucose level.

    Antitumor effect of the drug is noted in the initial stages of the disease - with active growth and metastasis, the progression of tumor growth is possible.

    Patients with high iron content should use minimal doses of the drug.

    Instructions
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