AC-glenvitol (AC-glenvitol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceAscorbic acid + Dextrose + SucroseAscorbic acid + Dextrose + Sucrose
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  • AC-glenvitol
    pills inwards 
    Glenmeri Biotechnological Enterprise FEZ - Bishkek LLC     Republic of Kyrgyzstan
    • Dosage form: & nbsppills
    Composition:

    Active components: ascorbic acid 25 mg sucrose (sugar) 2,064 g glucose (dextrose) 0.830 g

    Excipients: potato starch, citric acid, magnesium stearate, flavor identical to natural (orange 585, 590, cherry 95, 061, pear 95, 573 (duchesly 511), lemon 517, mint 614, black currant 522, 554. Food color: (Annato E 160 b), carmine (E 120), curcumin (E 100)).

    Description:

    - tablets of flat-cylindrical shape, with a bevel, without a fruit aroma - white. Light roughness and light marbling are allowed.

    - tablets of flat-cylindrical shape, with a bevel, with the orange flavor - orange. Light roughness and light marbling are allowed. Allowed blotches of a darker shade of color;

    - tablets of flat-cylindrical form, with a facet, with a cherry flavor - pink. Light roughness and light marbling are allowed. Allowed blotches of a darker shade of color;

    - tablets of flat-cylindrical shape, with a bevel, with a pear flavor (duchessa) - green or yellow-green in color. Light roughness and light marbling are allowed.Allowed blotches of a darker shade of color;

    - tablets of flat-cylindrical shape, with a bevel, with a lemon flavor - yellow or yellow-green color. Light roughness and light marbling are allowed. Allowed blotches of a darker shade of color;

    - tablets of flat-cylindrical shape, with a bevel, with mint aroma - white. Light roughness and light marbling are allowed;

    - tablets of flat-cylindrical shape, with a bevel, with the aroma of black currant - pink-lavender color. Light roughness and light marbling are allowed. Blurs of a darker shade of color are allowed.

    Pharmacotherapeutic group:Vitamin
    ATX: & nbsp

    A.11.G.B   Ascorbic acid in combination with other drugs

    Pharmacodynamics:Ascorbic acid plays an important role in the regulation of oxidation-reduction processes, carbohydrate metabolism, blood clotting, tissue regeneration, and improves the body's resistance. Ascorbic acid (vitamin C) is not formed in the human body, but comes only with food. With a balanced and nutritious diet, a person does not experience a deficiency in vitamin C.
    Indications:Prevention and treatment of Vitamin C hypovitaminosis.When the body needs vitamin C; in the period of active growth in children, pregnancy, breastfeeding, with increased physical and mental stress, fatigue, stressful conditions, during recovery after long and severe diseases.
    Contraindications:

    Hypersensitivity to the components of the drug. Do not administer large doses to patients with high blood coagulability, thrombophlebitis and a tendency to thrombosis, as well as diabetes and conditions accompanied by high blood sugar.

    Carefully:Persons with a deficiency of glucose-6-phosphate dehydrogenase.
    Pregnancy and lactation:

    The minimum daily requirement for ascorbic acid in II-III trimesters of pregnancy - about 60 mg.

    The minimum daily requirement for breastfeeding is 80 mg. A mother's diet containing an adequate amount of ascorbic acid is sufficient to prevent vitamin C deficiency in an infant (it is recommended not to exceed the maximum monthly requirement for ascorbic acid in the nursing mother).
    Dosing and Administration:

    The drug is taken orally after a meal.

    With the preventive purpose of appoint:

    Adults - 50-100 mg / day; Children 25 mg / day. During pregnancy and lactation, 300 mg / day. for 10-15 days, then for 100 mg / day.

    With a therapeutic purpose appoint:

    Adults - 50-100 mg 3-5 times a day; children 50-100 mg 2-3 times a day. The duration of treatment depends on the nature and course of the disease and is recommended by a doctor.

    Side effects:

    Allergic reactions to the components of the drug, irritation of the mucous membrane of the gastrointestinal tract (nausea, vomiting, diarrhea, stomach cramps), when used in high doses - hyperoxaluria and the formation of urinary stones from calcium oxalate; oppression of the insular pancreas function (hyperglycemia, glucosuria).

    Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia.

    Overdose:

    Symptoms with prolonged use of large doses (more than 1 g) are headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, hyperacid gastritis, ulceration of the gastrointestinal mucosa, heartburn, diarrhea, difficulty urinating, staining urine red ,hemolysis (in patients with deficiency of glucose-6-phosphate dehydrogenase), suppression of the function of the insulin pancreas apparatus (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (calcium oxalate), glomerular renal injury, moderate pollakiuria ).

    Reduced permeability of capillaries (possibly deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathies).
    Interaction:

    Increases the concentration in the blood of benzylpenicillin and tetracyclines; in a dose of 1 g / day increases the bioavailability of ethinyl estradiol. Improves absorption in the intestines of iron preparations (converts trivalent iron into bivalent); can increase the excretion of iron with simultaneous application with deferoxamine.

    Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline drink reduce absorption and absorption. With simultaneous application with ASA, urinary excretion of ascorbic acid increases and ASA excretion decreases. ASA reduces the absorption of ascorbic acid by about 30%. Increases the risk of developing crystalluria in the treatment of short-acting salicylates and sulfonamides, slows the excretion of acids by the kidneys, increases the excretion of drugs that have an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood. Increases the total clearance of ethanol, which, in turn, reduces the concentration of ascorbic acid in the body. Preparations of quinoline series (fluoroquinolones, etc.), calcium chloride, salicylates, glucocorticosteroids with long-term use deplete the stores of ascorbic acid. With simultaneous use reduces the chronotropic effect of isoprenaline. With prolonged use or use in high doses, it can disrupt the interaction of disulfiram-ethanol. In high doses increases the renal excretion of mexiletine. Barbiturates and primidon increase the excretion of ascorbic acid in the urine.

    Reduces the therapeutic effect of antipsychotic drugs (phenothiazine derivatives), tubular reabsorption of amphetamine and tricyclic antidepressants.
    Special instructions:

    In connection with the stimulating effect of ascorbic acid on the synthesis of glucocorticosteroid hormones, it is necessary to monitor the function of the adrenal glands and arterial pressure.With prolonged use of large doses, oppression of the insulin function of the pancreas is possible, so during treatment it must be regularly monitored. In patients with elevated iron levels in the body, ascorbic acid should be used in minimal doses. Assigning ascorbic acid to patients with rapidly proliferating and intensely metastatic tumors can aggravate the course of the process. Ascorbic acid, as a reductant, can distort the results of various laboratory tests (blood glucose, bilirubin, transaminase activity, LDH).

    Form release / dosage:

    Tablets 25 mg; tablets of 25 mg (orange, cherry, pear, lemon, mint, black currant).

    Packaging:

    For 10 tablets in parchment or waxed paper with subsequent wrapping in a label of cellophane or paraffined paper.

    For 12 tablets in a contoured cell packaging made of polyvinylchloride film, aluminum foil printed lacquered or paper laminated or film polymer laminated.

    2 contour mesh packages along with the instruction for use are placed in a pack of cardboard.

    For 2 or 4 tablets in a contour non-jammed package of paper laminated, or a film of polymeric laminated.

    For 5 contour non-jammed packages of 4 tablets or 10 contour non-jawed packages of 2 tablets, together with the instruction for use are placed in a pack of cardboard box.

    Before packing in a cardboard box, packages of cellophane or paraffined paper are packed in polyethylene bags of 50 packages.

    For 100 - 500 packages of cellophane or paraffined paper with an equal number of instructions for medical use or packs with contour mesh or cell-free packaging, put in a cardboard box.
    Storage conditions:

    In a dry place.

    Keep out of the reach of children.

    Shelf life:

    1 year. Do not use the drug after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-001922/08
    Date of registration:18.03.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:Glenmeri Biotechnological Enterprise FEZ - Bishkek LLC Glenmeri Biotechnological Enterprise FEZ - Bishkek LLC Republic of Kyrgyzstan
    Manufacturer: & nbsp
    Information update date: & nbsp26.04.2017
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