From the gastrointestinal tract: nausea, vomiting, diarrhea, pain in the epigastric region, intestinal colic, dyspepsia, flatulence, anorexia, constipation; at In rare cases, erosive and ulcerative lesions, bleeding and perforation of the gastrointestinal tract (hematemesis, melena), stomatitis at including aphthous, pancreatitis.
From the nervous system: Sometimes there is headache, dizziness, sleep disturbances (insomnia or drowsiness), excitement, in some cases marked sensitivity disorders, disorientation, memory, vision, hearing, taste, tinnitus, convulsions, irritability, tremor, depression, anxiety, vertigo, aseptic meningitis, paresthesia.
Allergic manifestations: sometimes there is a skin rash, seldom - hives, individual cases of eczema, polymorphic erythema, erythroderma, rarely had attacks of bronchial asthma; systemic anaphylactic reactions, in some cases, vasculitis, pneumonitis, Stevens-Johnson syndrome and Lyell syndrome, anaphylactic shock.
From the side of the kidneys: rarely peripheral edema, in some cases, acute renal failure, interstitial nephritis, nephrotic syndrome, hematuria, proteinuria.
From the side of the liver: transient increase in transaminase activity in the blood, rarely - hepatitis, in some cases fulminant hepatitis.
On the part of the hematopoiesis system: leukopenia, described individual cases of thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia.
From the cardiovascular system: single cases of tachycardia, hypertension, congestive heart failure, IHD.