Symptoms: bradycardia, arrhythmia, circulatory insufficiency, lowering blood pressure, hypertensive crisis, respiratory depression, delirium, acute hypoxia.
Treatment: with bradycardia - the introduction of 0.3-0.6 mg of atropine,arrhythmias - correction of blood gases, circulatory failure and hypotension - introduction of plasma or plasma-means, depth decrease or cessation of general anesthesia, with hyperthermal Stroke - cessation of inhalation, the increased supply of oxygen introduction antipyretics, correction of the water-salt balance and metabolic acidosis , if necessary, dantrolene (1 mg / kg) IV drip and continue the administration until the symptoms of the crisis disappear (maximum total dose of 10 mg / kg).
To prevent recurrence of the crisis for 1 -3 days after the operation, dantrolen is administered orally or IV (4-8 mg / kg / day in 4 divided doses). Respiratory depression or inadequate ventilation postoperative necessitated dose reduction anesthetic (if it is used), airway and mechanical ventilation. In the case of delirium development, after the withdrawal from general anesthesia, small doses of the narcotic analgesic are administered.