Bungei® (Bengay®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceMethylsalicylate + RacetenolMethylsalicylate + Racetenol
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  • Bungei®
    cream externally 
    Johnson & Johnson, LLC     Russia
  • Bom-Bengue
    ointment externally 
    PHARMSTANDART-PHYTOPHARM-NN, LLC     Russia
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    ointment externally 
    TVERSKAYA PHARMACEUTICAL FACTORY, OJSC     Russia
    • Dosage form: & nbspcream for external use
    Composition:Composition (per 1 g of cream):

    Active substances: methylsalicylate - 150 mg; racemtol - 100 mg;

    Excipients: stearic acid 130 mg, glyceryl monostearate 80 mg, lanolin anhydrous 20 mg, sorbitan trioleate (polysorbate 85) 20 mg, sorbitan tristearate (span 65) 10 mg, trolamine (triethanolamine) 10 mg, purified water 480 mg.

    Description:White homogeneous cream with a characteristic odor.
    Pharmacotherapeutic group:Anti-inflammatory agent for topical application
    ATX: & nbsp

    M.02.A.C   Preparations containing derivatives of salicylic acid

    Pharmacodynamics:

    It causes muscle relaxation, increases blood flow, facilitates the removal of irritating metabolic products (primarily lactic acid), and also increases the duration physical exercises due to the heating effect and improves their portability.

    Racetenthol

    The irritating effect of racemetol helps reduce pain. The local action is accompanied by the expansion of the vessels, causing a sensation of cooling, turning into a feeling of slight burning and tingling, followed by an analgesic effect.

    Methylsalicylate

    Methylsalicylate - anti-inflammatory analgesic. Nonselectively inhibits cyclooxygenase, reducing the synthesis of prostaglandins. Normalizes increased permeability capillaries, improves microcirculation processes, reduces edema and infiltration of inflamed tissues

    Pharmacokinetics:

    With external application, the concentration of racemetol in the systemic circulation is negligible. Methyl salicylate, when applied externally, penetrates the tissues through unchanged skin, while analgesic concentration in the systemic blood flow is not achieved. The action is only local. The salicylates are excreted mainly by the kidneys, the rate of excretion depends on the plasma concentration and pH of the urine.

    Indications:
    • to reduce pain and stiffness in joints and muscles in case of injuries, sprains and inflammation
    • to reduce pain in the lower back
    • with myalgia (muscle pain) before and after sports.
    Contraindications:
    • hypersensitivity to any component of the drug
    • Violation of the integrity of the skin and inflammatory diseases of the skin at the site of application
    • children under 12 years old
    • pregnancy (III trimester)
    Carefully:

    • pregnancy (I - II trimester)

    • breast-feeding

    • intolerance to salicylates

    • Reye's syndrome

    Dosing and Administration:

    Outwardly. Apply the cream a thin layer directly on the painful area and gently rub until completely absorbed. If necessary, the procedure is repeated every few hours (up to 3-4 times a day) for 10 days.

    Side effects:

    Often (≥1/10), often (≥1/100, <1/10), infrequently (≥1/1000, <1/100), rarely (≥1/10000, <1/1000), very rarely (<1/10000).

    Postmarketing data:

    Impaired immune system: angioedema (very rare).

    Disturbances from the respiratory system, chest and mediastinum: shortness of breath in the context of hypersensitivity (very rarely). General disorders and disorders at the site of administration: reactions at the site of application (including blisters, burning, flushing, erythema, irritation, pain, paresthesia, urticaria, pruritus and rash) (very rarely). Injuries, intoxications and complications of manipulation: burns in the place of application (very rarely).

    Overdose:

    Overdose of racemetol and methyl salicylate was observed in some cases, mainly in children, with the occasional ingestion of drugs containing these substances.

    Overdosing with external application is rare and only when the drug is misused (applying to mucous membranes, to large areas of damaged or infected skin). Overdose Symptoms methylsalicylate: excitation,

    an increase in the depth of breathing, hyperpyrexia.

    Overdose Symptoms racemetol: nausea, pain in

    stomach, vomiting and symptoms of central nervous system depression such as dizziness, unstable gait, "tides" of blood to the face, drowsiness, respiratory depression and coma.

    Treatment: symptomatic and supporting; correction

    electrolyte and water balance, the purpose of adsorbing agents and saline laxatives, forced diuresis, external cooling of the body; at severe cases - blood transfusion, hemodialysis.

    Interaction:

    The drug causes flushing of the skin and reflexes the circulation blood in the subcutaneous tissue, such co-application with other preparations of the local action can lead to their absorption. In patients, sensitive to acetylsalicylic acid, with external application methyl salicylate allergic reactions, as well as angioedema.

    When combined with acetylsalicylic acid can there are toxic effects of salicylates.

    In patients using anticoagulants, for example, warfarin, bleeding may occur, since this drug contains salicylate.

    Special instructions:

    For external use only.

    Do not use with occlusive dressings, warming compresses. When irritation of the skin application. Avoid getting into eyes, on the mucous membranes, on areas of skin irritation. If pain persists for 10 days or more, and the cream is not causes relief of the condition, it is necessary to see a doctor.

    A cross-allergy to other salicylates.

    Do not use in children under the age of 12 years!

    If the medication came in worthlessness do not throw it in waste water or on the street! Place medicinal product in a package and put in the trash. These measures will help to protect the Wednesday!

    Effect on the ability to drive transp. cf. and fur:Can not exert influence on the ability to drive and control machinery
    Form release / dosage:Cream for external use
    Packaging:Aluminum tube. 50 grams of cream in an aluminum tube with a screwed polypropylene cap. 1 tuba together with instructions for use in a cardboard bundle.
    Storage conditions:At a temperature of no higher than 25 ° C. Keep out of the reach of children!
    Shelf life:2 years.
    Terms of leave from pharmacies:Without recipe
    Registration number:П N011925 / 01
    Date of registration:25.02.2011 / 17.10.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:Johnson & Johnson, LLC Johnson & Johnson, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspJohnson & Johnson LLC Johnson & Johnson LLC Russia
    Information update date: & nbsp22.01.2017
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