Bloktran - instructions for use, doses, side effects, contraindications

core: lactose monohydrate 4.0 mg, microcrystalline cellulose 48.0 mg, povidone (polyvinylpyrrolidone, povidone K-17) 1.4 mg, potato starch 27.5 mg, carboxymethyl starch sodium (sodium starch glycolate) 7.0 mg, magnesium stearate - 0.7 mg, silicon dioxide colloid (aerosil) - 1.4 mg;

shell: Hypromellose (hydroxypropylmethylcellulose) 3.234 mg, copovidone 0.420 mg, titanium dioxide (E 171) 1.064 mg, talc 1.077 mg, polysorbate 80 (twin 80) 0.700 mg, dye sunset yellow (water-soluble) (E 110 ) (Indakol sunset yellow, synovitis yellow-orange 85) - 0.005 mg.

Pharmacotherapeutic group:Angiotensin II receptor antagonist

ATX: & nbsp

C.09.C.A.01 Losartan

C.09.C.A Angiotensin II antagonists

Pharmacodynamics:

A hypotensive drug, is a specific antagonist of angiotensin II receptors (subtype AT1). Does not inhibit kinase II - an enzyme that destroys bradykinin. Reduces the overall peripheral vascular resistance (OPSS), the concentration in the blood of adrenaline and aldosterone, blood pressure (BP), pressure in the small circle of the circulation; reduces afterload, has a diuretic effect. It interferes with the development of myocardial hypertrophy, increases tolerance to exercise in patients with heart failure. After a single dose, the hypotensive effect (decreases systolic and diastolic blood pressure) reaches a maximum after 6 hours, then gradually decreases within 24 hours.

The maximum hypotensive effect is achieved in 3-6 weeks after the start of the drug.

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Effect on the ability to drive transp. cf. and fur:

During the treatment period, care should be taken when driving vehicles and other potentially hazardous activities, as some of the side effects observed with losartan, such as dizziness,drowsiness can adversely affect the ability to drive a vehicle and carry out potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

Form release / dosage:Tablets, coated with a coating, 50 mg.

Packaging:10 pcs., - packings of cellular contour.

Storage conditions:Store in a dry place, at a temperature not exceeding 30 ° C.

Keep out of the reach of children.

Shelf life:3 years.

Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:LSR-000027

Date of registration:02.04.2007 / 21.10.2014

Expiration Date:Unlimited

The owner of the registration certificate:PHARMSTANDART-FORESTRY, OJSC PHARMSTANDART-FORESTRY, OJSC Russia

Manufacturer: & nbsp

PHARMSTANDART-FORESTRY, OJSC Russia

Information update date: & nbsp18.02.2017

Illustrated instructions

Instructions

Bloktran® (Bloctran®)